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논문 기본 정보

자료유형
학술저널
저자정보
Teahyen Cha (University of Ulsan) Jiyoon Jeong (University of Ulsan) Byong Sop Lee (University of Ulsan) Ellen Ai-Rhan Kim (University of Ulsan College of Medicine) Ki-Soo Kim (University of Ulsan College of Medicine) Euiseok Jung (University of Ulsan)
저널정보
대한주산의학회 Perinatology Perinatology Vol.32 No.3
발행연도
2021.9
수록면
125 - 132 (8page)

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Objective: The aim of this study was to determine whether there were differences in respiratory outcomes of extremely low gestational age neonates according to the surfactant without endotracheal tube intubation (SURE) technique or the intubation-surfactant-extubation (INSURE) technique in treating respiratory distress syndrome. Methods: Preterm infants less than 28 weeks of gestational age between January 2015 and December 2020 were retrospectively reviewed. Demographic and outcome variables, the respiratory outcomes including incidence of bronchopulmonary dysplasia (BPD) and pulmonary acuity score (PAS) were compared between the infants who received SURE and INSURE. Results: A total of 53 infants (SURE, 18; INSURE, 35) were analyzed. There were differences between SURE and INSURE groups in birth weight (919.5 g vs. 815.6 g, P=0.037) and Apgar score (1 minute: 6 vs. 5, P=0.037; 5 minutes: 8 vs. 7, P=0.016). Positive pressure ventilation rate at delivery room, continuous positive airway pressure failure rate, the second dose of surfactant administration, the duration of invasive and/or noninvasive respiratory support, and the incidence of BPD were not significantly different between the two groups. The PAS at 7 days of life (DOL) was lower than at birth in SURE group (P=0.048). However, there were no differences between PAS at birth and at postmenstrual age 36 weeks. Conclusion: Respiratory outcomes including incidence of BPD were not different between the SURE and INSURE groups. Nevertheless, PAS at 7 DOL decreased after the SURE technique.

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