지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 184 - 192 (9page)
- DOI
- https://doi.org/10.14802/jmd.21046
이용수
초록· 키워드
오류제보하기
There is an extensive debate on the neurological consequences of 2019 novel coronavirus disease (COVID-19) and its impact on Parkinson’s disease (PD) patients, which seems to puzzle neurologists. Links between viral infections and PD have long been suspected and studied, but the exact relationship remains elusive. Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the brain through multiple routes and has a direct impact on the brain, cumulative damage occurs due to the activation of proinflammatory cytokines and chemokines. SARS-CoV-2 seems to aggravate PD due to its effects on α-synuclein, mitochondrial dysfunction, and dopamine depletion. A few studies have even highlighted the higher vulnerability of PD patients to COVID-19. The sudden dramatic change in lifestyle caused by the pandemic and the widespread lockdowns that were implemented have added to the hidden sorrows of PD patients, as they already have a compromised mechanism for coping with stress. This review summarizes insights from basic science and the clinical effect of SARS-CoV-2 infection on the human brain, with a specific focus on PD.
목차
등록된 정보가 없습니다.
참고문헌 (66)
참고문헌 신청
Shahid Z / 2020 / COVID-19 and older adults : what we know / J Am Geriatr Soc 68:926~929
Bartel WP / 2020 / Parkinson’s disease. In: Gerlai RT. Behavioral and Neural Genetics of Zebrafish / Academic Press :377~412
Jang H / 2009 / Viral parkinsonism / Biochim Biophys Acta 1792:714~721
Beauchamp LC / 2020 / Parkinsonism as a third wave of the COVID-19 pandemic / J Parkinsons Dis 10:1343~1353
Jang H / 2012 / Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice / J Neurosci 32:1545~1559
Bartel WP / 2020 / Parkinson’s disease. In: Gerlai RT. Behavioral and Neural Genetics of Zebrafish / Academic Press :377~412
Jang H / 2009 / Viral parkinsonism / Biochim Biophys Acta 1792:714~721
Beauchamp LC / 2020 / Parkinsonism as a third wave of the COVID-19 pandemic / J Parkinsons Dis 10:1343~1353
Jang H / 2012 / Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice / J Neurosci 32:1545~1559
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Association of Substantia Nigra Degeneration with Poor Neurological Recovery in Basal Ganglia Infarctions
대한뇌졸중학회지
2023 .01
-
Presynaptic Dysfunction by Familial Factors in Parkinson Disease
International Neurourology Journal
2018 .01
-
Protease-Activated Receptor-2 Is Associated with Terminal Differentiation of Epidermis and Eccrine Sweat Glands
Annals of Dermatology
2015 .01
-
The effect of earplug training on noise protection
대한직업환경의학회지
2019 .12
-
Role of Coagulation Factor 2 Receptor during Respiratory Pneumococcal Infections
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016 .12
-
Age- and sex-relative effect of naringenin on substantia gelatinosa neurons of trigeminal subnucleus caudalis in immature mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
GABA- and glycine-mimetic responses of honokiol on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Action of citral on the substantia gelatinosa neurons of trigeminal subnucleus caudalis in juvenile mice
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Mitochondrial dynamics in substantia nigra of MPTP-induced non-human primate Parkinson’s disease model
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Mechanism of Lipid Accumulation through PAR2 Signaling in Diabetic Male Mice
Endocrinology and Metabolism
2021 .01
-
침 및 운동 치료로 호전된 파킨슨병 환자 1례에 대한 증례보고
대한한방내과학회지
2022 .10
-
Development of immunotherapy and nanoparticles-based strategies for the treatment of Parkinson’s disease
Journal of Pharmaceutical Investigation
2021 .01
-
Compression Myelopathy due to Proliferative Changes around C2 Pars Defects without Instability
Asian Spine Journal
2016 .01
-
MPTP로 유도된 Parkinson's disease 동물 모델에서 열다한소탕 가감방 (MYH)의 신경 세포 보호 효과
JSCM : Journal of Sasang constitutional medicine
2015 .01
-
Convolutional Neural Network-Based Automatic Segmentation of Substantia Nigra on Nigrosome and Neuromelanin Sensitive MR Images
Investigative Magnetic Resonance Imaging
2021 .09
-
Impact of deep brain stimulation on non-motor symptoms in Parkinson’s disease
Journal Of Movement Disorders
2024 .04
-
Validation of Pharyngeal Acid Reflux Episodes Using Hypopharyngeal Multichannel Intraluminal Impedance-pH
Journal of Neurogastroenterology and Motility (JNM)
2023 .01
-
Proteomic change by Korean Red Ginseng in the substantia nigra of a Parkinson’s disease mouse model
Journal of Ginseng Research
2018 .10
-
Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson's Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways
Biomolecules & Therapeutics(구 응용약물학회지)
2019 .01
-
Efficacy of Sublingual Immunotherapy for House Dust Mite-Induced Allergic Rhinitis: A Meta-Analysis of Randomized Controlled Trials
Allergy, Asthma & Immunology Research
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0