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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한백신학회 Clinical and Experimental Vaccine Research Clinical and Experimental Vaccine Research Vol.10 No.3
- 발행연도
- 2021.9
- 수록면
- 298 - 300 (3page)
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초록· 키워드
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We present the case of a 48-year-old Caucasian woman, who developed an acute urticarial rash after the second dose of coronavirus disease 2019 (COVID-19) vaccination with Oxford-AstraZeneca. Though the most common cutaneous adverse reactions to vaccines are non-allergic, we believe the rash may represent an immediate hypersensitivity type I reaction against the vaccine excipient Polysorbate 80 (Pol80), configuring an acute allergic urticaria. Skin prick test with Pol80, were performed and resulted positive, confirming the role of Pol80 in eliciting immediate hypersensitivity in our patient. Of note, sensitizing excipients contained in COVID-19 vaccines are commonly used in everyday products and preexisting sensitizations may cause allergic reactions to vaccines, highlighting the need to undergo allergy consultation upon vaccine administration.
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참고문헌 (7)
참고문헌 신청
Kounis NG / 2021 / Allergic reactions to current available COVID-19 vaccinations: pathophysiology, causality, and therapeutic considerations / Vaccines(Basel) 9:221
Chung EH / 2014 / Vaccine allergies / Clin Exp Vaccine Res 3:50~57
Fritsche PJ / 2010 / Vaccine hypersensitivity : update and overview / Swiss Med Wkly 140:238~246
Kim Mi-Ae / 2021 / COVID-19 Vaccine-associated Anaphylaxis and Allergic Reactions: Consensus Statements of the KAAACI Urticaria/Angioedema/Anaphylaxis Working Group / Allergy, Asthma & Immunology Research 13(4):526~544
Perez-Perez L / 2011 / Biologic-induced urticaria due to polysorbate 80 : usefulness of prick test / Br J Dermatol 164:1119~1120
Chung EH / 2014 / Vaccine allergies / Clin Exp Vaccine Res 3:50~57
Fritsche PJ / 2010 / Vaccine hypersensitivity : update and overview / Swiss Med Wkly 140:238~246
Kim Mi-Ae / 2021 / COVID-19 Vaccine-associated Anaphylaxis and Allergic Reactions: Consensus Statements of the KAAACI Urticaria/Angioedema/Anaphylaxis Working Group / Allergy, Asthma & Immunology Research 13(4):526~544
Perez-Perez L / 2011 / Biologic-induced urticaria due to polysorbate 80 : usefulness of prick test / Br J Dermatol 164:1119~1120
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