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논문 기본 정보

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학술저널
저자정보
Kim Youlim (Division of Pulmonary Allergy and Critical Care Medicine Department of Internal Medicine Hallym Uni) Lee Hyun (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) Park Yeonkyung (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.Department of In) 정성준 (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) Yeo Yoomi (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) Park Tai Sun (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) 박동원 (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) 김상헌 (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) Kim Tae-Hyung (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) 손장원 (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) 윤호주 (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) Moon Ji-Yong (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.)
저널정보
대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research Allergy, Asthma & Immunology Research Vol.13 No.5
발행연도
2021.9
수록면
808 - 816 (9page)
DOI
10.4168/aair.2021.13.5.808

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Besides obesity, there are limited studies regarding the relationship between the individual components of metabolic syndrome and wheezing. It is largely unknown whether the co-existence of other metabolic syndrome components has additive effects on wheezing in the adult population. The association between the individual components of metabolic syndrome and current wheezing was evaluated in adults using data from the Korea National Health and Nutrition Examination Survey from 2008 to 2012. Subjects with metabolic syndrome more frequently had wheezing during the past 12 months (current wheezing) (adjusted odds ratio [aOR] = 1.56; 95% confidence interval [CI] = 1.37?1.77) and wheezing during exercise in the past 12 months (aOR = 1.59; 95% CI = 1.37?1.84). Of the individual metabolic syndrome components, central obesity (aOR = 1.48; 95% CI = 1.31?1.66) and low high-density lipoprotein (HDL) cholesterol (aOR = 1.18; 95% CI = 1.05?1.34) were significantly associated with current wheezing. There were no significant associations between the other components of metabolic syndrome (high triglyceride level, blood pressure, and fasting plasma glucose level) and the presence of current wheezing. In addition, the association was much higher when both central obesity and low HDL cholesterol were present together compared to when either of the conditions was present alone (aOR = 1.67; 95% CI = 1.44?1.94). There is a significant association between metabolic syndrome and current wheezing in Korean adults. Of the components of metabolic syndrome, low HDL cholesterol and central obesity are independently and additively associated with the increased rate of current wheezing.
#Metabolic syndrome #obesity #body mass index #lipoprotein #HDL #triglycerides #dyslipidemia #asthma #wheezing

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참고문헌 신청
Byung-Keun Kim / 2020 / Evaluation and Management of Difficult-to-Treat and Severe Asthma: An Expert Opinion From the Korean Academy of Asthma, Allergy and Clinical Immunology, the Working Group on Severe Asthma / Allergy, Asthma & Immunology Research 12(6):910~933 dbpia

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