Long-term Survival after Repeated Local Therapy and Salvage Chemotherapy for Recurrent Metastases from Gastric Cancer: a Case Report and Literature Review

권지현; 한혜숙; 김희경; 백승우; 양예원; 이기형; 손승명; 김원동; 김대훈; 윤효영

doi:https://doi.org/10.5230/jgc.2018.18.e26

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자료유형: 학술저널

저자정보: 권지현 (충북대학교) 한혜숙 (충북대학교) 김희경 (충북대학교) 백승우 (충북대학교병원) 양예원 (충북대학교) 이기형 (충북대학교) 손승명 (충북대학교병원) 김원동 (충북대학교) 김대훈 (충북대학교) 윤효영 (충북대학교)

저널정보: 대한위암학회 Journal of Gastric Cancer Journal of Gastric Cancer 제18권 제3호

발행연도: 2018.9

수록면: 305 - 312 (8page)

DOI: https://doi.org/10.5230/jgc.2018.18.e26

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We report a rare case of long-term survival in a patient who received local therapy and salvage chemotherapy for recurrent metastases, along with a literature review. A 65-year-old male patient underwent subtotal gastrectomy for advanced gastric adenocarcinoma. Six months after gastrectomy, 2 metastatic intra-abdominal lymph node enlargements were detected, which were treated with radiotherapy. At 55 months after gastrectomy, an abdominal wall mass was detected, which was treated by surgical resection. The patient received 5-fluorouracil/ leucovorin/irinotecan chemotherapy for 27 months before and after radiotherapy and docetaxel chemotherapy for 6 months after surgical resection of the abdominal wall metastasis. At the last visit, 7.8 years since the initial resection of the primary gastric cancer and 6.2 years since detection of the first metastases, the patient was disease-free and required no further chemotherapy. This case suggests that repeated local therapy offers potential for long-term survival in a carefully selected subset of patients with recurrent metastases.

#Chemotherapy #Gastric cancer #Metastasis #Radiotherapy #Surgery

참고문헌 (16)

참고문헌 신청

이준행 / 2014 / Clinical Practice Guidelines for Gastric Cancer in Korea: An Evidence-Based Approach / Journal of Gastric Cancer 14(2):87~104

Bang YJ / 2010 / Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial / Lancet 376:687~697

Tanai C / 2010 / A case of long-term survival after surgical resection of solitary pulmonary metastasis from gastric cancer / Jpn J Clin Oncol 40:85~89

Fumagalli U / 2010 / Adrenal metastases from adenocarcinoma of the esophagogastric junction: adrenalectomy and long-term survival / Updates Surg 62:63~67

Choi YJ / 2018 / Long-term survival after gastrectomy and metastasectomy for gastric cancer with synchronous bone metastasis / World J Gastroenterol 24:150~156

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