Natural History of Early Gastric Cancer: a Case Report and Literature Review

Tomohiro Iwai; Masao Yoshida; Hiroyuki Ono; Naomi Kakushima; Kohei Takizawa; Masaki Tanaka; Noboru Kawata; Sayo Ito; Kenichiro Imai; Kinichi Hotta; Hirotoshi Ishiwatari; Hiroyuki Matsubayashi

doi:https://doi.org/10.5230/jgc.2017.17.e9

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자료유형: 학술저널

저자정보: Tomohiro Iwai (Shizuoka Cancer Center) Masao Yoshida (Shizuoka Cancer Center) Hiroyuki Ono (Shizuoka Cancer Center) Naomi Kakushima (Shizuoka Cancer Center) Kohei Takizawa (Shizuoka Cancer Center) Masaki Tanaka (Shizuoka Cancer Center) Noboru Kawata (Shizuoka Cancer Center) Sayo Ito (Shizuoka Cancer Center) Kenichiro Imai (Shizuoka Cancer Center) Kinichi Hotta (Shizuoka Cancer Center) Hirotoshi Ishiwatari (Shizuoka Cancer Center) Hiroyuki Matsubayashi (Shizuoka Cancer Center)

저널정보: 대한위암학회 Journal of Gastric Cancer Journal of Gastric Cancer 제17권 제1호

발행연도: 2017.3

수록면: 88 - 92 (5page)

DOI: https://doi.org/10.5230/jgc.2017.17.e9

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Early detection and treatment decrease the mortality rate associated with gastric cancer (GC). However, the natural history of GC remains unclear. An 85-year-old woman was referred to our hospital for evaluation of a gastric tumor. Esophagogastroduodenoscopy identified a 6 mm, flat-elevated lesion at the lesser curvature of the antrum. A biopsy specimen showed a well-differentiated tubular adenocarcinoma. The depth of the lesion was estimated to be intramucosal. Although the lesion met the indications for endoscopic resection, periodic endoscopic follow-up was performed due to the patient's advanced age and comorbidities. The mucosal GC invaded into the submucosa 3 years later, and finally progressed to advanced cancer 5 years after the initial examination. The patient died of tumor hemorrhage 6.4 years after the initial examination. In this case, mucosal GC progressed to advanced GC, eventually leading to the patient's death from GC. Early and appropriate treatment is required to prevent GC-related death.

#Early gastric cancer #Natural history

참고문헌 (15)

참고문헌 신청

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Marchet A / 2011 / Validation of the new AJCC TNM staging system for gastric cancer in a large cohort of patients (n = 2,155): focus on the T category / Eur J Surg Oncol 37:779~785

Nashimoto A / 2013 / Gastric cancer treated in 2002 in Japan : 2009 annual report of the JGCA nationwide registry / Gastric Cancer 16:1~27

Sekiguchi M / 2013 / Favorable long-term outcomes of endoscopic submucosal dissection for locally recurrent early gastric cancer after endoscopic resection / Endoscopy 45:708~713

Isomoto H / 2009 / Endoscopic submucosal dissection for early gastric cancer : a large-scale feasibility study / Gut 58:331~336

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