지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 419 - 424 (6page)
- DOI
- 10.5021/ad.2021.33.5.419
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초록· 키워드
오류제보하기
Background Background: While microscopy (MS) evaluation of skin scrapings has a 100% positive predictive value and specificity by definition for scabies diagnosis, it has low sensitivity. Dermoscopy (DS) has not yet been widely accepted for diagnosis, and long-term clinician training is required.
Objective To evaluate the diagnostic validity of cytochrome c oxidase subunit 1 (cox1) gene nested polymerase chain reaction (PCR) as an adjunctive method for diagnosing scabies.
Methods This was a prospective, single institution study, conducted on a total of 302 skin lesions from 50 patients suspected of scabies at Kangdong Sacred Heart Hospital in Seoul, Korea. DS, MS, and cox1 nested PCR were performed on all patients.
Results Of the 302 lesions, 145 (48.0%) were obtained at first visit and 157 (52.0%) were identified in the course of follow-up visits after treatment. For all lesions, DS and MS sensitivity levels were 55.9% (73/136) and 55.2% (75/136), respectively, with cox1 gene nested PCR considered as 100%. The results of DS and MS identification showed no difference between each other and showed significant difference from that of cox1 gene nested PCR.
Conclusion Nested PCR detecting cox1 may be prospectively used to comprehensively diagnose lesions of scabies in clinical practice.
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Hengge UR / 2006 / Scabies : a ubiquitous neglected skin disease / Lancet Infect Dis 6:769~779
Pannell RS / 2005 / The incidence of molluscum contagiosum, scabies and lichen planus / Epidemiol Infect 133:985~991
Walton SF / 2007 / Problems in diagnosing scabies, a global disease in human and animal populations / Clin Microbiol Rev 20:268~279
Prins C / 2004 / Dermoscopy for the in vivo detection of sarcoptes scabiei / Dermatology 208:241~243
Dupuy A / 2007 / Accuracy of standard dermoscopy for diagnosing scabies / J Am Acad Dermatol 56:53~62
Pannell RS / 2005 / The incidence of molluscum contagiosum, scabies and lichen planus / Epidemiol Infect 133:985~991
Walton SF / 2007 / Problems in diagnosing scabies, a global disease in human and animal populations / Clin Microbiol Rev 20:268~279
Prins C / 2004 / Dermoscopy for the in vivo detection of sarcoptes scabiei / Dermatology 208:241~243
Dupuy A / 2007 / Accuracy of standard dermoscopy for diagnosing scabies / J Am Acad Dermatol 56:53~62
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