지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제25권 제2호
- 발행연도
- 2021.6
- 수록면
- 118 - 128 (11page)
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초록· 키워드
오류제보하기
Purpose: To investigate the value of MR textural analysis, including use of diffusion weighted imaging (DWI) to differentiate malignant from benign soft-tissue tumors on 3T MRI.
Materials and Methods: We enrolled 69 patients (25 men, 44 women, ages 18 to 84 years) with pathologically confirmed soft-tissue tumors (29 benign, 40 malignant) who underwent pre-treatment 3T-MRI. We calculated MR texture, including mean, standard deviation (SD), skewness, kurtosis, mean of positive pixels (MPP), and entropy, according to different spatial-scale factors (SSF, 0, 2, 4, 6) on axial T1- and T2-weighted images (T1WI, T2WI), contrast-enhanced T1WI (CE-T1WI), high b-value DWI (800 sec/mm2 ), and apparent diffusion coefficient (ADC) map. We used the Mann-Whitney U test, logistic regression, and area under the receiver operating characteristic curve (AUC) for statistical analysis.
Results: Malignant soft-tissue tumors had significantly lower mean values of DWI, ADC, T2WI and CE-T1WI, MPP of ADC, and CE-T1WI, but significantly higher kurtosis of DWI, T1WI, and CE-T1WI, and entropy of DWI, ADC, and T2WI than did benign tumors (P < 0.050). In multivariate logistic regression, the mean ADC value (SSF, 6) and kurtosis of CE-T1WI (SSF, 4) were independently associated with malignancy (P ≤ 0.009). A multivariate model of MR features worked well for diagnosis of malignant soft-tissue tumors (AUC, 0.909).
Conclusion: Accurate diagnosis could be obtained using MR textural analysis with DWI and CE-T1WI in differentiating benign from malignant soft-tissue tumors
목차
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참고문헌 (24)
참고문헌 신청
World Health Organization / 2002 / Pathology and genetics of tumors of soft tissue / IARC Press :12~224
Surov A / 2015 / Comparison of ADC values in different malignancies of the skeletal musculature : a multicentric analysis / Skeletal Radiol 44:995~1000
Razek A / 2012 / Assessment of soft tissue tumours of the extremities with diffusion echoplanar MR imaging / Radiol Med 117:96~101
Ahlawat S / 2019 / Magnetic resonance imaging biomarkers in musculoskeletal soft tissue tumors: review of conventional features and focus on nonmorphologic imaging / J Magn Reson Imaging 50:11~27
Kransdorf MJ / 2013 / Imaging of soft-tissue tumors / Lippincott Williams & Wilkins
Surov A / 2015 / Comparison of ADC values in different malignancies of the skeletal musculature : a multicentric analysis / Skeletal Radiol 44:995~1000
Razek A / 2012 / Assessment of soft tissue tumours of the extremities with diffusion echoplanar MR imaging / Radiol Med 117:96~101
Ahlawat S / 2019 / Magnetic resonance imaging biomarkers in musculoskeletal soft tissue tumors: review of conventional features and focus on nonmorphologic imaging / J Magn Reson Imaging 50:11~27
Kransdorf MJ / 2013 / Imaging of soft-tissue tumors / Lippincott Williams & Wilkins
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