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논문 기본 정보

자료유형
학술저널
저자정보
박소현 (제주대학교병원) 최진현 (제주대학교병원) 김진성 (연세대학교 의과대학) 안소현 (연세대학교 의과대학) 이호 (연세대학교 의과대학) 최서희 (연세대학교 의과대학) 박광우 (연세대학교 의과대학) 김민주 (연세대학교 의과대학)
저널정보
한국의학물리학회 의학물리 의학물리 제29권 제1호
발행연도
2018.3
수록면
1 - 7 (7page)
DOI
https://doi.org/10.14316/pmp.2018.29.1.1

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초록· 키워드

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The TomoTherapy® beam-delivery method creates helical beam-junctioning patterns in the dose distribution within the target. In addition, the dose discrepancy results in the particular region where the resonance by pattern of dose delivery occurs owing to the change in the position and shape of internal organs with a patient’s respiration during long treatment times. In this study, we evaluated the dose pattern of the longitudinal profile with the change in respiration. The superior-inferior motion signal of the programmable respiratory motion phantom was obtained using AbChes as a four-dimensional computed tomography (4DCT) original moving signal. We delineated virtual targets in the phantom and planned to deliver the prescription dose of 300 cGy using field widths of 1.0 cm, 2.5 cm, and 5.0 cm. An original moving signal was fitted to reflecting the beam delivery time of the TomoTherapy®. The EBT3 film was inserted into the phantom movement cassette, and static, without the movement and with the original movement, was measured with signal changes of 2.0 s, 4.0 s, and 5.0 s periods, and 2.0 mm and 4.0 mm amplitudes. It was found that a dose fluctuation within ±4.0% occurred in all longitudinal profiles. Compared with the original movement, the region of the gamma index above 1 partially appeared within the target and the border of the target when the period and amplitude were changed. Gamma passing rates were 95.00% or more. However, cases for a 5.0 s period and 4.0 mm amplitude at a field width of 2.5 cm and for 2.0 s and 5.0 s periods at a field width of 5.0 cm have gamma passing rates of 92.73%, 90.31%, 90.31%, and 93.60%. TomoTherapy® shows a small difference in dose distribution according to the changes of period and amplitude of respiration. Therefore, to treat a variable respiratory motion region, a margin reflecting the degree of change of respiration signal is required.

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