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학술저널
저자정보
백진혁 (계명대학교) 강성일 (영남대학교) 류지원 (서울대학교) 임성윤 (분당서울대학교병원) Ryu Ji Young (Department of Internal Medicine Seoul National University Bundang Hospital Seongnam Korea.) Son Hyung Eun (Department of Internal Medicine Seoul National University Bundang Hospital Seongnam Korea.) Jeong Jong Cheol (Seoul National University Bundang Hospital) 진호준 (서울대학교) 나기영 (서울대학교) 채동완 (서울대학교) 강성범 (Department of Surgery Seoul National University Bundang Hospital Seongnam Korea) Kim Sejoong (Seoul National University Bundang Hospital)
저널정보
대한신장학회 Kidney Research and Clinical Practice Kidney Research and Clinical Practice Vol.40 No.4
발행연도
2021.12
수록면
634 - 644 (11page)
DOI
10.23876/j.krcp.21.002

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Background: A laparoscopic approach is widely used in abdominal surgery. Although several studies have compared surgical and on- cological outcomes between laparoscopic surgery (LS) and open surgery (OS) in rectal cancer patients, there have been few studies on postoperative renal outcomes. Methods: We conducted a retrospective cohort study involving 1,633 patients who underwent rectal cancer surgery between 2003 and 2017. Postoperative acute kidney injury (AKI) was diagnosed according to the serum creatinine criteria of the Kidney Disease: Im- proving Global Outcomes classification. Results: Among the 1,633 patients, 1,072 (65.6%) underwent LS. After matching propensity scores, 395 patients were included in each group. The incidence of postoperative AKI in the LS group was significantly lower than in the OS group (9.9% vs. 15.9%; p = 0.01). Operation time, estimated blood loss, and incidence of transfusion in the LS group were significantly lower than those in the OS group. Cox proportional hazard models revealed that LS was associated with decreased risk of postoperative AKI (hazard ratio [HR], 0.599; 95% confidence interval [CI], 0.402?0.893; p = 0.01) and postoperative transfusion was associated with increased risk of AKI (HR, 2.495; 95% CI, 1.529?4.072; p < 0.001). In the subgroup analysis, the incidence of postoperative AKI in patients with middle or high rectal cancer who underwent LS was much lower than in those who underwent OS (HR, 0.373; 95% CI, 0.197?0.705; p = 0.002). Conclusion: This study showed that LS may have a favorable effect on the development of postoperative AKI in patients with rectal cancer.

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