지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 472 - 483 (12page)
- DOI
- 10.23876/j.krcp.21.020
이용수
초록· 키워드
오류제보하기
Background: Peritoneal dialysis (PD) is improving as a renal replacement therapy for end-stage renal disease (ESRD) patients. We analyzed the main outcomes of PD over the last three decades at a single large-scale PD center with an established high-quality care system.
Methods: As a retrospective cohort study, we included participants (n = 1,203) who began PD between 1990 and 2019. Major PD-related outcomes were compared among the three 10-year cohorts.
Results: The 1,203 participants were 58.3% male with a mean age of 47.9 ± 13.8 years. The median PD treatment duration was 45 months (interquartile range, 19?77 months); 362 patients (30.1%) transferred to hemodialysis, 289 (24.0%) received kidney trans- plants, and 224 (18.6%) died. Overall, the 5- and 8-year adjust patient survival rates were 64% and 49%, respectively. Common caus- es of death included infection (n = 55), cardiac (n = 38), and cerebrovascular (n = 17) events. The 5- and 8-year technique survival rates were 77% and 62%, respectively, with common causes of technique failure being infection (42.3%) and solute/water clearance problems (22.7%). The 5-year patient survival significantly improved over time (64% for the 1990?1999 cohort vs. 93% for the 2010?2019 cohort). The peritonitis rate also substantially decreased over time, from 0.278 episodes/patient-year (2000?2004) to 0.162 episodes/patient-year (2015?2019).
Conclusion: PD is an effective treatment option for ESRD patients. There was a substantial improvement in the patient survival and peritonitis rates over time. Establishing adequate infrastructure and an effective system for high-quality PD therapy may be warranted to improve PD outcomes.
목차
등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Bello AK / 2019 / Status of care for end stage kidney disease in countries and regions worldwide: international cross sectional survey / BMJ 367:l5873
Korevaar JC / 2003 / Effect of starting with hemodialysis compared with peritoneal dialysis in patients new on dialysis treatment : a randomized controlled trial / Kidney Int 64:2222~2228
Heaf JG / 2002 / Initial survival advantage of peritoneal dialysis relative to haemodialysis / Nephrol Dial Transplant 17:112~117
Weinhandl ED / 2010 / Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients / J Am Soc Nephrol 21:499~506
Lukowsky LR / 2013 / Comparing mortality of peritoneal and hemodialysis patients in the first 2 years of dialysis therapy : a marginal structural model analysis / Clin J Am Soc Nephrol 8:619~628
Korevaar JC / 2003 / Effect of starting with hemodialysis compared with peritoneal dialysis in patients new on dialysis treatment : a randomized controlled trial / Kidney Int 64:2222~2228
Heaf JG / 2002 / Initial survival advantage of peritoneal dialysis relative to haemodialysis / Nephrol Dial Transplant 17:112~117
Weinhandl ED / 2010 / Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients / J Am Soc Nephrol 21:499~506
Lukowsky LR / 2013 / Comparing mortality of peritoneal and hemodialysis patients in the first 2 years of dialysis therapy : a marginal structural model analysis / Clin J Am Soc Nephrol 8:619~628
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