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자료유형
학술저널
저자정보
김효민 (경북대학교) 윤창호 (경북대학교) 고혜진 (경북대학교) 이선화 (경북대학교) 이유미 (경북대학교)
저널정보
대한가정의학회 Korean Journal of Family Medicine Korean Journal of Family Medicine 제38권 제4호
발행연도
2017.7
수록면
233 - 238 (6page)

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Background: Persistent organic pollutants (POPs) are toxic materials that cannot be broken down naturally and that easily accumulate in the body. Although several studies have attempted to uncover the effects of POPs on the endocrine and nervous systems and on cancer, few focus on the relationship between low-dose POPs and public health. Here, we attempt to determine the relationship between the level of POPs and common gastrointestinal symptoms, including abdominal discomfort, diarrhea, and constipation.Methods: We recruited 121 subjects who visited Kyungpook National University Medical Center for health screen-ing. Plasma concentrations were evaluated for 40 kinds of POPs including 17 types of polychlorinated biphenyls (PCBs) and 23 types of organochlorine pesticides (OCP). Furthermore, the Korean version of the Rome III criteria was used to identify gastrointestinal symptoms.Results: Based on our results, abdominal discomfort showed an inverse relationship with several PCBs and an in-verted U-shaped relationship with several other OCPs including pp-DDD and pp-DDT. The effects of pp-DDD and pp-DDT on abdominal discomfort were similar to those of OCPs on obesity and metabolic syndrome.Conclusion: Our results suggest that mild and unspecified gastrointestinal symptoms with no clear causes could be related to POP levels.

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