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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제51권 제4호
- 발행연도
- 2017.7
- 수록면
- 422 - 427 (6page)
- DOI
- https://doi.org/10.4132/jptm.2016.11.11
이용수
초록· 키워드
오류제보하기
Mammary carcinoma arising in microglandular adenosis (MGA) is extremely rare, and MGA is regarded as a non-obligate precursor of triple-negative breast cancer. We report five cases of carcinoma arising in MGA of the breast. All cases showed a spectrum of proliferative lesions ranging from MGA to atypical MGA, ductal carcinoma in situ or invasive carcinoma. Immunohistochemically, all cases were triple-negative and expression of S-100 protein gradually decreased as the lesions progressed from MGA to atypical MGA and carcinoma. Three cases showed acinic cell differentiation with reactivity to α1-antitrypsin, and one case was metaplastic carcinoma. During clinical follow-up, one patient developed local recurrence. Carcinoma arising in MGA is a rare but distinct subset of triple-negative breast cancer with characteristic histologic and immunohistochemical findings.
목차
등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
Rosen PP / 2001 / Rosen’s breast pathology / Lippincott Williams & Wilkins
Rosenblum MK / 1986 / Is microglandular adenosis a precancerous disease? A study of carcinoma arising therein / Am J Surg Pathol 10:237~245
Koenig C / 2000 / Carcinoma arising in microglandular adenosis : an immunohistochemical analysis of 20 intraepithelial and invasive neoplasms / Int J Surg Pathol 8:303~315
Khalifeh IM / 2008 / Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma / Am J Surg Pathol 32:544~552
Shui R / 2011 / Matrix-producing carcinoma of the breast in the Chinese population: a clinicopathological study of 13 cases / Pathol Int 61:415~422
Rosenblum MK / 1986 / Is microglandular adenosis a precancerous disease? A study of carcinoma arising therein / Am J Surg Pathol 10:237~245
Koenig C / 2000 / Carcinoma arising in microglandular adenosis : an immunohistochemical analysis of 20 intraepithelial and invasive neoplasms / Int J Surg Pathol 8:303~315
Khalifeh IM / 2008 / Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma / Am J Surg Pathol 32:544~552
Shui R / 2011 / Matrix-producing carcinoma of the breast in the Chinese population: a clinicopathological study of 13 cases / Pathol Int 61:415~422
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