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Comprehensive Review of Domestic and Foreign Biomonitoring Programs and Current Status of Bio-sample Application
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국내외 바이오모니터링 프로그램 및 생체시료 활용 현황

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Type
Academic journal
Author
Da Hae Kim (세종대학교 바이오융합공학과) Sungkyoon Kim (서울대학교 보건대학원) Seungho Lee (아주대학교 의과대학 직업환경의학과) Choi Yoon-Hyeong (가천대학교) Jin Hee Kim (세종대학교 바이오융합공학과)
Journal
Korean Society of Envlromental Health 한국환경보건학회지 한국환경보건학회지 제47권 제3호 KCI Excellent Accredited Journal
Published
2021.6
Pages
205 - 226 (22page)
DOI
10.5668/JEHS.2021.47.3.205

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Comprehensive Review of Domestic and Foreign Biomonitoring Programs and Current Status of Bio-sample Application
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Objectives: Biomonitoring programs have been widely implemented in the field of environmental health, both in Korea and worldwide. Recently, it has been suggested that the storage, management, and utilization of bio?samples collected from biomonitoring programs should be organized based on a biobank system. Therefore, we attempted to review the current status of representative biomonitoring programs and biobank systems that have been implemented in Korea and in other countries. Methods: We searched for bio-samples collected in domestic and foreign biomonitoring programs and their applications. For this, we referred to research papers, homepages hosted by biomonitoring programs, and project reports. We also checked information for biobanks related with biomonitoring programs, including the operating systems, facilities, technologies, and regulations of biobanks. Results: We summarized six domestic and 32 foreign biomonitoring programs. These biomonitoring programs collected bio-samples to determine the relationship between environmental chemicals and diseases. Domestically, bio-samples from KoNEHS, KorSEP, MOCEH, KoCHENS, and KorEHS-C were stored at ?80o C in a deep freezer at the National Institute of Environmental Research, while KNHANES samples were stored at Korea Biobank, which has a stabilized biobanking system with a well-established database. Nine foreign biomonitoring programs (JECS, China-NHBP, CKB, CHMS, NHANES, GerES, Germaan ESB, MoBa, and UK Biobank) were ongoing for large populations. Among them, CKB, GermanESB, and UK biobank have been maintained for at least 10 years with their own biomonitoring programs as well as advanced systems for the safe storage of bio-samples. Conclusion: Currently on-going biobanks have devoted considerable efforts to managing bio-samples for public purposes. The preceding domestic and foreign biomonitoring programs and biobanks will be great references for constructing biobank facilities and systems for environmental public health in Korea in the future.

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