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논문 기본 정보

자료유형
학술저널
저자정보
이인혜 (용인대학교 자연과학연구소) 나진성 (한국생산기술연구원) 지경희 (용인대학교)
저널정보
한국환경보건학회 한국환경보건학회지 한국환경보건학회지 제47권 제1호
발행연도
2021.2
수록면
1 - 19 (19page)
DOI
10.5668/JEHS.2021.47.1.1

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초록· 키워드

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Objectives: Phthalates, which are widely used as plasticizers, have been recognized as endocrine disruptors. In the present study, we provided information on the regulation of these chemicals and summarized the information available on their detection and toxicity in children’s products and those of their alternatives. Methods: The regulatory frameworks related to phthalates in children’s products in Korea, the United States (US), and the European Union (EU) were compared. Data on the detection concentration of 16 phthalates and seven phthalate alternatives that could be used in polyvinyl chloride (PVC) plastic products for children as well as on their toxicity classification and endocrine disruption toxicity were collected from the literature. Results: Korea adopted US and EU chemical standards for six phthalates (DEHP, BBP, DBP, DINP, DIDP, and DNOP), but not others (e.g., DIBP, DPP, DHP, and DCHP). Among the ten phthalates and seven substitutes for which regulatory standards were not determined, DIBP, DHP, DEHA, DIBA, DINA, and DEHT were detected in children’s products made from PVC plastic. DIBP and DHP, which have a reproductive toxicity classification of 1B, were frequently detected in PVC toys. The reproductive toxicity, estrogenicity, and anti-androgenic activity of the unregulated phthalates and their alternatives have been reported in diverse in vitro and in vivo assays. Conclusion: The use of unregulated phthalates and their substitutes in children’s products is increasing. Further monitoring and toxicological information on phthalate alternatives is required to develop proper management plans.

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