지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제47권 제6호
- 발행연도
- 2017.11
- 수록면
- 521 - 530 (10page)
이용수
초록· 키워드
오류제보하기
Gold nanoparticles (AuNPs) are ‘smart nanomaterials’ with a variety of applications in the different fields. The conventional methods used for AuNPs have some drawbacks and therefore, search of an alternative ‘green method’ is of high importance. In this study, Acinetobacter baumannii AB01 isolated from an infected apple sample was used as a green route for AuNPs synthesis.
Effect of various physicochemical parameters such as pH, temperature, cell density and gold chloride salt concentrations on AuNPs synthesis was studied. These AuNPs were further characterized by UV?Vis spectrophotometer, transmission electron microscopy (TEM), energy dispersive spectroscopy, X-ray diffraction and dynamic light scattering. TEM images study showed presence of an extracellular polymeric substance around cells of A. baumannii AB01. The synthesized biogenic AuNPs were tested for their antibacterial activity by well diffusion method. Anti-biofilm efficacy of AuNPs was tested on the glass slide surfaces against the biofilms of Pseudomonas aeruginosa, Vibrio cholera and Brevibacterium linens and visualised by using a fluorescence microscopy. Biofilm formation was reduced about 60?80 % when compared with control biofilm (without AuNPs). Effect of different AuNPs concentrations on biofilm formation in microtiter plates was studied by 96-well plate assay. The bacterial biofilm inhibition (%) was increased with increasing concentrations of AuNPs.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Bankar A / 2010 / Banana peel extract mediated synthesis of gold nanoparticles / Colloids Surf B : Biointerf 80:45~50
Berlau J / 1999 / Isolation of Acinetobacter spp. including A. baumannii from vegetables: implications for hospital-acquired infections / J Hosp Infect 42:201~204
Beveridge J / 1981 / Binding of metals to cell envelopes of Escherichia coli K.-12 / Appl Environ Microbiol 14:325~335
Brayner R / 2007 / Cyanobacteria as Bioreactors for the synthesis of Au, Ag, Pd, and Pt nanoparticles via an enzyme-mediated route / J Nanosci Nanotechnol 7:2696~2708
Chaw C / 2005 / Role of silver ions in destabilization of intermolecular adhesion forces measured by atomic force microscopy in Staphylococcus epidermidis biofilms / Antimicrob Agents Chemother 49:4853~4859
Berlau J / 1999 / Isolation of Acinetobacter spp. including A. baumannii from vegetables: implications for hospital-acquired infections / J Hosp Infect 42:201~204
Beveridge J / 1981 / Binding of metals to cell envelopes of Escherichia coli K.-12 / Appl Environ Microbiol 14:325~335
Brayner R / 2007 / Cyanobacteria as Bioreactors for the synthesis of Au, Ag, Pd, and Pt nanoparticles via an enzyme-mediated route / J Nanosci Nanotechnol 7:2696~2708
Chaw C / 2005 / Role of silver ions in destabilization of intermolecular adhesion forces measured by atomic force microscopy in Staphylococcus epidermidis biofilms / Antimicrob Agents Chemother 49:4853~4859
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