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논문 기본 정보

자료유형
학술저널
저자정보
Chun-Han Wu (Tri-Service General Hospital School of Medicine National Defense Medical Center) Chung-Kan Peng (Tri-Service General Hospital School of Medicine National Defense Medical Center) Chi-Hsian Chung (Tri-Service General Hospital National Defense Medical Center) Wu-Chien Chien (Tri-Service General Hospital National Defense Medical Center) Nian-Sheng Tzeng (Tri-Service General Hospital School of Medicine National Defense Medical Center)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제19권 제4호
발행연도
2022.4
수록면
247 - 258 (12page)
DOI
10.30773/pi.2021.0277

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Objective There is limited clarity concerning the risk of dementia after pneumonia with intensive care unit (ICU) stay. We conducted a nationwide cohort study, which aimed to investigate the impact of dementia after pneumonia with and without intensive care unit admission.Methods Data was obtained from Taiwan’s National Health Insurance Research Database between 2000 and 2015. A total of 7,473 patients were identified as having pneumonia required ICU stay, along with 22,419 controls matched by sex and age. After adjusting for confounding factors, multivariate Cox regression model analysis was used to compare the risk of developing dementia during the 15-years follow-up period.Results The enrolled pneumonia patients with ICU admission had a dementia rate of 9.89%. Pneumonia patients without ICU admission had a dementia rate of 9.21%. The multivariate Cox regression model analysis revealed that the patients with ICU stay had the higher risk of dementia, with a crude hazard ratio of 3.371 (95% confidence interval, 3.093?3.675; p<0.001).Conclusion This study indicated that pneumonia with ICU stay is associated with an increased risk of dementia. A 3-fold risk of dementia was observed in patients admitted to the ICU compared to the control group.

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