지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.4
- 수록면
- 87 - 96 (10page)
- DOI
- 10.3341/kjo.2021.0095
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초록· 키워드
오류제보하기
Purpose: To investigate the efficacy of outpatient clinic-based sutureless amniotic membrane transplantation (AMT) alongwith therapeutic contact lens (T-lens) application in eyes with persistent epithelial defects (PED).Methods: Nine eyes of nine patients (mean age, 71.7 ± 5.2 years) diagnosed with PED and treated with in-office suturelessAMT combined with T-lens application were retrospectively reviewed. Demographics, systemic diseases, PED etiology, cornealepithelial defect size, visual acuity, corneal scraping culture results, and clinical course were evaluated.Results: Among nine eyes with PED, three had neurotrophic keratopathy, four had infectious keratitis (three with fungal keratitisand one with bacterial keratitis), one had limbal deficiency, and one had marginal keratitis. The mean epithelial defectsize (calculated as an average of the horizontal and vertical diameters) was 3.13 ± 1.42 mm, and the mean duration from AMTto epithelial healing was 30.1 ± 10.5 days (range, 14?51 days) in successful trials. The success rates were 77.8% (7/9) per patientand 66.7% (8/12) per trial. The causes of failure in two patients were AMT displacement and uncontrolled infection.Conclusions: Our results demonstrate that in-office sutureless AMT combined with T-lens application can be used in patientswith PED who are refractory to medications. It will be especially helpful for elderly patients because of its easy-to-use method.To achieve successful outcomes with AMT, an appropriate periocular environment as well as infection control need to beconsidered.
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