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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.2
- 수록면
- 22 - 29 (8page)
- DOI
- 10.5213/inj.2040468.234
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초록· 키워드
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Purpose: To determine the risk factors predicting upper urinary tract (UUT) damage using a grading system for upper uri nary tract dilation (UUTD) and a descriptive system for all urinary tract dysfunction (AUTD) in patients with myelodyspla sia.
Methods: Six hundred thirty-seven patients with myelodysplasia were evaluated at our center from January 2008 to Novem ber 2019. Clinical data, ultrasonography, magnetic resonance urography, and video-urodynamics (VUDS) parameters were collected. Univariate and multivariate analyses were used to determine the risk factors predicting UUT damage.
Results: Three hundred eighty-three males and 254 females were included. The average course of lower urinary tract symp toms (LUTS) was 14.08±7.07 years (range, 3?31 years). The urodynamic diagnoses of all patients were as follows: detrusor overactivity, 26.8%; detrusor underactivity, 6.44%; and acontractile detrusor, 66.72%. UUT damage was determined in 66.56% of the patients. Of the patients, 28.73 % had vesicoureteral reflux (VUR) during filling (bilateral, n=50; unilateral, n=133) on fluoroscopy during VUDS testing. Two hundred thirty-four patients had UUTD (bilateral, n=203; unilateral, n=31). The oc currence of hydronephrosis based on ultrasonography was closely related to ipsilateral VUR (P<0.05). Absent of bladder sen sation, long-term course of LUTS, decreased maximum cystometric capacity (MCC) and bladder compliance (BC), and in creased postvoid residual urine (PVR) were shown to be independent risk factors in logistic regression analysis.
Conclusions: This retrospective study using UUTD and AUTD systems indicated that patients with myelodysplasia have a high incidence of UUT damage. Absence of bladder sensation, long-term course of LUTS, decreased MCC and BC, and in creased PVR were independent risk factors predicting UUT damage.
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