지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.11
- 수록면
- 1 - 11 (11page)
- DOI
- https://doi.org/10.3802/jgo.2022.33.e71
이용수
초록· 키워드
오류제보하기
Objective: The recently updated World Health Organization classification divides endocervical adenocarcinomas (ADCs) into human papillomavirus (HPV)-associated (HPVA) and HPV-independent (HPVI) ADCs. This study aimed to investigate the differences in the clinical features and treatment outcomes between patients with HPVA and HPVI.
Methods: We retrospectively reviewed the electronic medical records and pathology slides of 123 patients with endocervical ADC who underwent radical hysterectomy and adjuvant radiation therapy. Tumor characteristics, patterns of failure, and survival outcomes were compared between HPVA and HPVI ADCs.
Results: Eighty-one (65.9%) and 42 (34.1%) patients were diagnosed with HPVA and HPVI ADCs, respectively. HPVI ADC showed more frequent positive vaginal resection margin (VRM) and peritoneal seeding than HPVA ADC. After a median follow-up of 58.1 months, local recurrence and distant metastasis were more frequently observed in HPVI ADC than in HPVA ADC. Both local recurrence-free survival (77.3% vs. 91.8%) and distant metastasis-free survival (50.1% vs. 73.7%) rates of HPVI ADC were lower than those of HPVA ADC. Disease- free survival was not significantly different between HPVI and HPVA ADCs.
Conclusion: We demonstrated that HPVI ADC exhibited higher rates of VRM involvement and peritoneal seeding than those of HPVA ADC, resulting in higher rates of local recurrence and distant metastasis. Further studies with larger populations are warranted to explore optimal treatment strategies based on the histological subtypes of endocervical ADC.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Evaluation of human papillomavirus (HPV) prediction using the International Endocervical Adenocarcinoma Criteria and Classification system, compared to p16 immunohistochemistry and HPV RNA in-situ hybridization
Journal of Pathology and Translational Medicine
2020 .01
-
Endocervical Adenocarcinoma In Situ Phenotype with Ovarian Metastasis
Journal of Pathology and Translational Medicine
2019 .01
-
Gastric type mucinous endocervical adenocarcinoma of the uterine cervix: very rare and interesting case
Obstetrics & Gynecology Science
2018 .01
-
Correlation between EGFR Expression and Radiosensitivity in Cervical Adenocarcinoma Cases
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Significance of serum CA125 level in surgically resected cervical adenocarcinoma with adverse features
Journal of Gynecologic Oncology
2021 .09
-
Focus on The Radiotherapy
대한외과학회 학술대회 초록집
2019 .10
-
Selective Radiotherapy after Distant Metastasis of Nasopharyngeal Carcinoma Treated with Dose-Dense Cisplatin plus Fluorouracil
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Prognostic Evaluation of Tumor-Stroma Ratio in Patients with Early Stage Cervical Adenocarcinoma Treated by Surgery
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
A case of extremely early cervical adenocarcinoma diagnosed only by endocervical curettage with macroscopic pelvic lymph node metastases
Obstetrics & Gynecology Science
2019 .01
-
New strategy for pancreatic ductal adenocarcinoma with peritoneal metastasis
한국간담췌외과학회 학술대회지
2016 .04
-
Retrospective study on factors affecting the prognosis in oral cancer patients who underwent surgical treatment only
Maxillofacial Plastic Reconstructive Surgery
2016 .01
-
The baseline recurrence risk of patients with intermediate-risk cervical cancer
Obstetrics & Gynecology Science
2021 .01
-
Role of Radiotherapy: Indications and Outcomes of Radiotherapy before and after Conversion Surgery
대한외과학회 학술대회 초록집
2021 .11
-
Adverse effect of excess body weight on survival in cervical cancer patients after surgery and radiotherapy
Radiation oncology journal : ROJ
2017 .01
-
Association between obesity and local control of advanced rectal cancer after combined surgery and radiotherapy
Radiation oncology journal : ROJ
2016 .01
-
Outcome of Palliative and Radical Radiotherapy in Patients with Oral Squamous Cell Carcinoma - a Retrospective Study
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Definitive radiotherapy with or without chemotherapy for clinical stage T4N0-1 non-small cell lung cancer
Radiation oncology journal : ROJ
2015 .01
-
전립선암의 방사선치료
대한의사협회지
2015 .01
-
Intracranial Hemangiopericytomas : A Retrospective Study of 15 Patients with a Special Review of Recurrence
대한신경외과학회지
2015 .01
-
Circulating tumor cells (CTCs) represented early recurrence of distant metastasis and peritoneal dissemination in patients who underwent curative resection for pancreatic ductal adenocarcinoma
대한외과학회 학술대회 초록집
2019 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0