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논문 기본 정보

자료유형
학술저널
저자정보
Smriti Bohara (Mahidol University) Jackrit Suthakorn (Mahidol University)
저널정보
한국생체재료학회 생체재료학회지 생체재료학회지 제26권 제3호
발행연도
2022.9
수록면
357 - 373 (17page)
DOI
https://doi.org/10.1186/s40824-022-00269-3

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The use of orthopedic implants in surgical technology has fostered restoration of physiological functions. Along with successful treatment, orthopedic implants suffer from various complications and fail to offer functions correspondent to native physiology. The major problems include aseptic and septic loosening due to bone nonunion and implant site infection due to bacterial colonization. Crucial advances in material selection in the design and development of coating matrixes an opportunity for the prevention of implant failure. However, many coating materials are limited in in-vitro testing and few of them thrive in clinical tests. The rate of implant failure has surged with the ncreasing rates of revision surgery creating physical and sensitive discomfort as well as economic burdens. To overcome critical path ogenic activities several systematic oating techniques have been developed offering excellent results that combat infection and enhance bone integration. This review article includes some more common mplant coating matrixes with excellent in vitro and in vivo results focusing on infection rates, causes, complications, coating materials, host immune responses and significant research gaps. This study provides a comprehensive overview of potential coating technology, with functional combination coatings which are focused on ultimate clinical practice with substantial improvement on in-vivo tests. This includes the development of rapidly growing hydrogel coating techniques with the potential to generate several accurate and precise coating procedures.

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