지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.6
- 수록면
- 260 - 271 (12page)
- DOI
- https://doi.org/10.1186/s40824-022-00259-5
이용수
초록· 키워드
오류제보하기
Background: Stent-graft-induced inflammation is an independent risk factor for adverse aortic remodeling in aortic dissection. In this context, we asked that whether a methylprednisolone-loaded stent-graft could reduce inflamma tion and degradation. Methods: First, a coaxial electrospinning technique was used to create a core-shell film with methylprednisolone encapsulated in the inner of poly (L-lactide-co-caprolactone) nanofibers for controllable drug release. Second, an in vitro study was conducted to evaluate the biocompatibility of the nanofiber meshes. Third, the porcine aortic dis section model was developed to investigate the therapeutic effects of the ethylprednisolone-loaded stent-graft. Results: The results demonstrated that the nanofiber-coated film with a methylprednisolone-poly-caprolactone core layer and a poly (L-lactide-co-caprolactone) shell layer could effectively sustain drug release in vitro. In vivo study showed that the methylprednisolone-loaded stent-graft could reduce degradtion of aortic dissection by regulating inflammation. Conclusions: Overall, the controllable drug release by coaxial nanofiber is a promising approach to alleviate aortic inflammation and promote aortic remodeling after stent-graft implantation.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Clinical pattern and anatomic causes of graft limb occlusion after bifurcated aortic stent grafting
대한외과학회 학술대회 초록집
2017 .11
-
Clinical outcomes of in situ graft reconstruction in treating infected abdominal aortic stent grafts following endovascular aortic aneurysm repair: a single-center experience
Annals of Surgical Treatment and Research
2023 .06
-
Mid-term Outcomes of Thoracic Endovascular Aortic Repair (TEVAR) in Acute Complicated Type B Aortic Dissection: A Comprehensive Analysis of Aortic Remodeling Patterns
Vascular Specialist International
2024 .09
-
Coxiella Burnetii Infection of Aortic Stent Graft
대한외과학회 학술대회 초록집
2018 .11
-
Iliac Artery Rupture and Retroperitoneal Migration of a Stent Graft during Transcatheter Aortic Valve Replacement
Korean Circulation Journal
2019 .01
-
Effect of Aortic Wall Stiffness to Endoleak after Endovascular Abdominal Aortic Aneurysm Repair: Preliminary Report
대한외과학회 학술대회 초록집
2018 .11
-
Management of Thoracic Aortic Injury after Blunt Trauma: Nine Cases at a Single Medical Center
Journal of trauma and injury : JTI
2016 .01
-
3D Printing Model before and after Transcatheter Aortic Valve Implantation for a Better Understanding of the Anatomy of Aortic Root
Korean Circulation Journal
2016 .01
-
Anatomical feasibility of fenestrated stent graft to treat complex abdominal aortic aneurysms from a Korean single institute database
Annals of Surgical Treatment and Research
2023 .01
-
Transcriptomic analyses of sclerotic aortic valves from hyperlipidemic Ldlr knockout mice
한국실험동물학회 학술발표대회 논문집
2019 .01
-
Reintervention Risk Factors and Survival Outcome in Ruptured Infrarenal Abdominal Aortic Aneurysm
대한외과학회 학술대회 초록집
2021 .11
-
Severe Aortic Stenosis Associated with Unicommissural Unicuspid Aortic Valve in a Middle Aged Male
Journal of Cardiovascular Imaging
2016 .01
-
STEMI equivqlent 심전도 소견을 동반한 근위부 대동맥박리 1예
한국응급구조학회지
2020 .01
-
Thoracoabdominal Aortic Dissection with Aortic and Common Femoral Aneurysm inducing Below-Knee Acute Limb Ischemia: A Case Report
대한외과학회 학술대회 초록집
2019 .10
-
Prospective Multicenter Study of the Challenges Inherent in Using Large Cell-Type Stents for Bilateral Stent-in-Stent Placement in Patients with Inoperable Malignant Hilar Biliary Obstruction
Gut and Liver
2018 .01
-
Rescue Technique for Malposition Caused by Mislabeled Stent Graft in Thoracic Aneurysm
Vascular Specialist International
2017 .01
-
Serial Vascular Responses of Balloon-Expandable Stent With Biodegradable Film-Type Graft in a Rabbit Iliac Artery Dissection Model (BioGard Study)
Korean Circulation Journal
2024 .08
-
State-of-the-Art Stent Technology to Minimize the Risk of Stent Thrombosis and In-Stent Restenosis: Abluminal-Coated Biodegradable Polymer Drug-Eluting Stent
Korean Circulation Journal
2022 .05
-
Analysis of trends and prospects regarding stents for human blood vessels
생체재료학회지
2018 .03
-
Stent-graft를 이용한 Peripheral 및 Visceral angioplasty의 증례 보고
대한인터벤션영상기술학회지
2022 .05
이 논문의 저자 정보
최근 본 자료
댓글(0)
0