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논문 기본 정보

자료유형
학술저널
저자정보
Seyyed Mojtaba Mousavi (National Taiwan University of Science and Technology) Gity Behbudi (University of Mohaghegh Ardabili) Ahmad Gholami (Biotechnology Research Center Shiraz University of Medical Sciences) Seyyed Alireza Hashemi (University of British Columbia) Zohre Mousavi Nejad (Biotechnology Research Center, Shiraz University of Medical Sciences) Sonia Bahrani (Biotechnology Research Center, Shiraz University of Medical Sciences) Wei-Hung Chiang (National Taiwan University of Science and Technology) Lai Chin Wei (Nanotechnology & Catalysis Research Centre, University of Malaya) Navid Omidifar (Shiraz University of Medical Sciences)
저널정보
한국생체재료학회 생체재료학회지 생체재료학회지 제26권 제1호
발행연도
2022.3
수록면
12 - 31 (20page)
DOI
https://doi.org/10.1186/s40824-022-00252-y

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Zinc nanostructures (ZnONSs) have attracted much attention due to their morphological, physicochemical, and electrical properties, which were entailed for various biomedical applications such as cancer and diabetes treatment, anti-inflammatory activity, drug delivery. ZnONS play an important role in inducing cellular apoptosis, triggering excess reactive oxygen species (ROS) production, and releasing zinc ions due to their inherent nature and specific shape. Therefore, several new synthetic organometallic method has been developed to prepare ZnO crystalline nanostructures with controlled size and shape. Zinc oxide nanostructures’ crystal size and shape can be controlled by simply changing the physical synthesis condition such as microwave irradiation time, reaction temperature, and TEA concentration at reflux. Physicochemical properties which are determined by the shape and size of ZnO nanostructures, directly affect their biological applications. These nanostructures can decompose the cell membrane and accumulate in the cytoplasm, which leads to apoptosis or cell death. In this study, we reviewed the various synthesis methods which affect the nano shapes of zinc particles, and physicochemical properties of zinc nanostructures that determined the shape of zinc nanomaterials. Also, we mentioned some macromolecules that controlled their physicochemical properties in a green and biological approaches. In addition, we present the recent progress of ZnONSs in the biomedical fields, which will help centralize biomedical fields and assist their future research development.

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