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Prevalence trends of non-alcoholic fatty liver disease among young men in Korea: A Korean military population- based cross-sectional study
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논문 기본 정보

Type
Academic journal
Author
Jaejun Lee (Department of Internal Medicine Armed Forces Goyang Hospital) Taeyun Kim (Department of Internal Medicine Armed Forces Goyang Hospital) Hyun Yang (The Catholic University Liver Research Center College of Medicine The Catholic University of Korea) Si Hyun Bae (The Catholic University Liver Research Center College of Medicine The Catholic University of Korea)
Journal
대한간학회 Clinical and Molecular Hepatology Clinical and Molecular Hepatology 제28권 제2호 KCI Accredited Journals
Published
2022.4
Pages
196 - 206 (11page)
DOI
10.3350/cmh.2021.0371

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Prevalence trends of non-alcoholic fatty liver disease among young men in Korea: A Korean military population- based cross-sectional study
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Background/Aims: Non-alcoholic fatty liver disease (NAFLD) has become a major concern in Korea since its emergence as a dominant cause of chronic liver disease. However, no study has explored its prevalence in adults under 30 years of age. Therefore, we performed a cross-sectional study to investigate the prevalence of NAFLD in Korean men in their early 20s. Methods: We collected data of 596,359 Korean soldiers who participated in a health examination between January 2015 and July 2021. A total of 571,872 individuals were analyzed after excluding those with missing data and hepatitis B antigen positivity. Hepatic steatosis was determined using the hepatic steatosis index (HSI). Participants with HSI >36 were considered to have NAFLD. Results: All participants were men, and the mean age was 20.9±1.3 years. Of the 571,872 participants screened, 77,020 (13.47%) were classified as having NAFLD. The prevalence of NAFLD consistently increased from 2015 to 2021 (10.66% vs. 16.44%, P<0.001). Increases from 2015 to 2021 were also noted in the prevalence of hypercholesterolemia, hyperglycemia, and hypertension (P<0.001 for all). The mean body mass index also increased from 23.3±3.0 kg/m2 to 23.9±3.1 kg/m2 between 2015 and 2021 (P<0.001). Conclusions: The prevalence of NAFLD and of other metabolic dysfunctions in Korean men in their early 20s increased from 2015 to 2021.

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