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논문 기본 정보

자료유형
학술저널
저자정보
안기훈 (고려대학교) 김혜인 (고려대학교) 이광식 (고려대학교 안암병원 AI센터) 허주선 (고려대학교) 김호연 (고려대학교) 조금준 (고려대학교) 홍순철 (고려대학교) 오민정 (고려대학교) 김해중 (독립연구자)
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제65권 제6호
발행연도
2022.11
수록면
487 - 501 (15page)
DOI
https://doi.org/10.5468/ogs.22060

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ObjectiveThis study systematically analyzed coronavirus disease 2019 (COVID-19) and vaccination details during pregnancy byusing the national health insurance claims data. MethodsPopulation-based retrospective cohort data of 12,399,065 women aged 15-49 years were obtained from the KoreaNational Health Insurance Service claims database between 2019 and 2021. Univariate analysis was performed tocompare the obstetric outcomes of pregnant women (ICD-10 O00-O94) and their newborns (ICD-10 P00-P96) with andwithout COVID-19. Univariate analysis was also performed to compare the age and obstetric outcomes of pregnantwomen receiving different types of vaccines. ResultsThe percentage of pregnant women with COVID-19 during pregnancy was 0.11%. Some obstetric outcomes of pregnantwomen with COVID-19, including the rates of preterm birth or cesarean delivery, were significantly better than thoseof pregnant women without COVID-19. The rate of miscarriage was higher in pregnant women with COVID-19 thanwithout COVID-19. However, the outcomes of newborns of women with and without COVID-19 were not significantlydifferent. Regarding vaccination type, obstetric outcomes of pregnant women appeared to be worse with the viralvector vaccine than with the mRNA vaccine. ConclusionTo the best of our knowledge, this is the first study to systematically analyze COVID-19 and vaccination details duringpregnancy using the national health insurance claims data in Korea. The obstetric outcomes in pregnant women withand without COVID-19 and their newborns were similar.

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