지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약리학회 The Korean Journal of Physiology & Pharmacology The Korean Journal of Physiology & Pharmacology 제26권 제1호
- 발행연도
- 2022.1
- 수록면
- 1 - 13 (13page)
- DOI
- 10.4196/kjpp.2022.26.1.1
이용수
초록· 키워드
오류제보하기
Kidney disease is becoming a global public health issue. Acute kidney injury (AKI) and chronic kidney disease (CKD) have serious adverse health outcomes.
However, there is no effective therapy to treat these diseases. Lactoferrin (LF), a multi-functional glycoprotein, is protective against various pathophysiological conditions in various disease models. LF shows protective effects against AKI and CKD.
LF reduces markers related to inflammation, oxidative stress, apoptosis, and kidney fibrosis, and induces autophagy and mitochondrial biogenesis in the kidney. Although there are no clinical trials of LF to treat kidney disease, several clinical trials and studies on LF-based drug development are ongoing. In this review, we discussed the possible kidney protective mechanisms of LF, as well as the pharmacological and therapeutic advances. The evidence suggests that LF may become a potent pharmacological agent to treat kidney diseases.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
T helper 17 cells in the pathophysiology of acute and chronic kidney disease
Kidney Research and Clinical Practice
2021 .01
-
Sonographic Growth Charts for Kidney Length in Normal Korean Children: A Prospective Observational Study
Journal of Korean Medical Science
2016 .01
-
Greenness and kidney? A review of epidemiological studies on the association between green space and kidney disease
Kidney Research and Clinical Practice
2024 .01
-
Recent Update on Acute Kidney Injury-to-Chronic Kidney Disease Transition
Yonsei Medical Journal
2024 .05
-
Recognizing the importance of physical activity on sarcopenia in chronic kidney disease
Osteoporosis and Sarcopenia
2022 .03
-
Clinical Significance of Acute Kidney Injury in Lung Cancer Patients
Cancer Research and Treatment
2021 .10
-
The association between acute kidney injury in renal infarction and progression to chronic kidney disease
Kidney Research and Clinical Practice
2016 .01
-
Risk Factors for the Progression of Chronic Kidney Disease in Children
Childhood Kidney Diseases
2021 .01
-
Cerebral Small Vessel Disease and Chronic Kidney Disease
대한뇌졸중학회지
2015 .01
-
Prevalence of Chronic Kidney Disease in Korea: the Korean National Health and Nutritional Examination Survey 2011-2013
Journal of Korean Medical Science
2016 .01
-
Use of mesenchymal stem cells for chronic kidney disease
Kidney Research and Clinical Practice
2019 .01
-
Mitochondrial dysfunction in kidney injury, inflammation, and disease: potential therapeutic approaches
Kidney Research and Clinical Practice
2020 .01
-
Intestinal microbiota and kidney diseases
Kidney Research and Clinical Practice
2021 .09
-
Pediatric Kidney Transplantation
Childhood Kidney Diseases
2021 .01
-
Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Acute Kidney Injury
대한외과학회 학술대회 초록집
2018 .11
-
Dorsal Spinal Ligamentum Flavum Thickening: A Magnetic Resonance Imaging Study
Asian Spine Journal
2018 .01
-
Clinical Significance of the Interval Change of Plasma Neutrophil Gelatinase-Associated Lipocalin in Acute Kidney Injury and Acute Kidney Injury Superimposed on Chronic Kidney Disease
전남의대학술지
2019 .01
-
Clinical Genetic Testing in Children with Kidney Disease
Childhood Kidney Diseases
2021 .01
-
신기능 저하 환자의 신경집중치료
Journal of Neurocritical Care
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0