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논문 기본 정보

자료유형
학술저널
저자정보
Seng Chan You (Yonsei University College of Medicine) Seongwon Lee (Ajou University School of Medicine) Byungjin Choi (Ajou University School of Medicine) Rae Woong Park (Ajou University School of Medicine)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.52 No.12
발행연도
2022.12
수록면
853 - 864 (12page)
DOI
https://doi.org/10.4070/kcj.2022.0294

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A retrospective observational study is one of the most widely used research methods in medicine. However, evidence postulated from a single data source likely contains biases such as selection bias, information bias, and confounding bias. Acquiring enough data from multiple institutions is one of the most effective methods to overcome the limitations. However, acquiring data from multiple institutions from many countries requires enormous effort because of financial, technical, ethical, and legal issues as well as standardization of data structure and semantics. The Observational Health Data Sciences and Informatics (OHDSI) research network standardized 928 million unique records or 12% of the world’s population into a common structure and meaning and established a research network of 453 data partners from 41 countries around the world. OHDSI is a distributed research network wherein researchers do not own or directly share data but only analyzed results. However, sharing evidence without sharing data is difficult to understand. In this review, we will look at the basic principles of OHDSI, common data model, distributed research networks, and some representative studies in the cardiovascular field using the network. This paper also briefly introduces a Korean distributed research network named FeederNet.

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