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논문 기본 정보

자료유형
학술저널
저자정보
Han Ick Park (Department of Oral and Maxillofacial Surgery Asan Medical Center College of Medicine University of) Jee-Ho Lee (Jee-Ho Lee and Sang Jin Lee contributed equally to this work. Department of Oral and Maxillofacial) Sang Jin Lee (Jee-Ho Lee and Sang Jin Lee contributed equally to this work. Wake Forest Institute for Regenerativ)
저널정보
대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제44권
발행연도
2022.1
수록면
1 - 13 (13page)
DOI
10.1186/s40902-022-00361-7

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BackgroundThe mandible is a functional bio-organ that supports facial structures and helps mastication and speaking. Large mandible defects, generally greater than 6-cm segment loss, may require composite tissue reconstruction such as osteocutaneous-vascularized free flap which has a limitation of additional surgery and a functional morbidity at the donor site. A 3D bio-printing technology is recently developed to overcome the limitation in the composite reconstruction of the mandible using osteocutaneous-vascularized free flap.ReviewScaffold, cells, and bioactive molecules are essential for a 3D bio-printing. For mandibular reconstruction, materials in a 3D bio-printing require mechanical strength, resilience, and biocompatibility. Recently, an integrated tissue and organ printing system with multiple cartridges are designed and it is capable of printing polymers to reinforce the printed structure, such as hydrogel.ConclusionFor successful composite tissue reconstruction of the mandible, biologic considerations and components should be presented with a comprehensive on-demand online platform model of customized approaches.

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