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논문 기본 정보

자료유형
학술저널
저자정보
Sherwani Nikita (Virology Lab Department of Microbiology Pt. JNM Medical College Raipur Chhattisgarh 492001 India) Singh Neha (Virology Lab Department of Microbiology Pt. JNM Medical College Raipur Chhattisgarh 492001 India) Neral Arvind (Department of Pathology Pt. JNM Medical College Raipur Chhattisgarh 492001 India) Jaiswal Jyoti (Department of Obstetrics and Gynaecology Pt. JNM Medical College Raipur 492001 Chhattisgarh India) Nagaria Tripti (Department of Obstetrics and Gynaecology Pt. JNM Medical College Raipur 492001 Chhattisgarh India) Khandwal Onkar (Department of Paediatrics Pt. JNM Medical College Raipur 492001 Chhattisgarh India)
저널정보
한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제32권 제9호
발행연도
2022.9
수록면
1,098 - 1,102 (5page)
DOI
10.4014/jmb.2206.06056

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The placenta is a captivating multifunctional organ of fetal origin and plays an essential role during pregnancy by intimately connecting mother and baby. This study explicates placental pathology and information about 25 placentas collected from the mothers infected with novel coronavirus (SARS-COV-2). So far, congenital transmission of SARS-CoV-2 seems to be remarkably uncommon in spite of many cases of COVID-19 during pregnancy. Out of the 25 placental tissue samples collected, none has shown gene expression of SARS-CoV-2 when confirmed by RT-PCR. At the same time, nasal and throat swab samples collected from newborns of SARS-CoV-2-positive mothers correspondingly tested negative by RT-PCR. The shielding properties of placental barriers against viral infections from mothers to newborns remains a mystery. Major histopathological findings have been recorded as choriodecidual tissue with necrosis, intramural fibrin deposition, chorionic villi with fibrosis, and calcification. Moreover, although recent findings are insufficient to prove direct placental transmission of COVID-19, the abundance of angiotensin-converting enzymes-2 (ACE-2) on the placental surface could potentially contribute to unpleasant outcomes during pregnancy as SARSCoV- 2 gains access to human cells via ACE-2. Finally, the significance of these findings is vague and needs further study.

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