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논문 기본 정보

자료유형
학술저널
저자정보
Jongwook Yu (Yonsei University College of Medicine) Jae Hee Cheon (Yonsei University College of Medicine)
저널정보
대한면역학회 Immune Network Immune Network Vol.22 No.6
발행연도
2022.12
수록면
1 - 28 (28page)

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초록· 키워드

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Gut dysbiosis is one of prominent features in inflammatory bowel diseases (IBDs) which are of an unknown etiology. Although the cause-and-effect relationship between IBD and gut dysbiosis remains to be elucidated, one area of research has focused on the management of IBD by modulating and correcting gut dysbiosis. The use of antibiotics, probiotics either with or without prebiotics, and fecal microbiota transplantation from healthy donors are representative methods for modulating the intestinal microbiota ecosystem. The gut microbiota is not a simple assembly of bacteria, fungi, and viruses, but a complex organlike community system composed of numerous kinds of microorganisms. Thus, studies on specific changes in the gut microbiota depending on which treatment option is applied are very limited. Here, we review previous studies on microbial modulation as a therapeutic option for IBD and its significance in the pathogenesis of IBD.

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ABSTRACT
INTRODUCTION
PATHOGENESIS OF IBD
ANTIBIOTICS AND MICROBIAL MODULATION
PROBIOTICS, PREBIOTICS, SYNBIOTICS, AND MICROBIAL MODULATION
FECAL MICROBIOTA TRANSPLANTATION AND MICROBIAL MODULATION
POSTBIOTICS AND MICROBIAL MODULATION
MICROBIAL MODULATION BY GENE DELIVERY USING MICROORGANISMS IN IBD
CONCLUSION
REFERENCES

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