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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.12
- 수록면
- 283 - 288 (6page)
- DOI
- 10.20307/nps.2020.26.4.283
이용수
초록· 키워드
오류제보하기
Microbial transformation of a potent progestin, norethisterone (17β-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one) (1) was carried out by using two filamentous fungi Aspergillus niger and Penicillium citrinum. Biotransformation of 1 with A. niger yielded a hydroxylated transformed product 10β,17β-diydroxy-19-nor-17α-pregn-4-en-20-yn-3-one (2) whereas 11β,17β-diydroxy-19-nor-17α-pregn-4-en-20-yn-3-one (3) was obtained through microbial transformation of 1 by P. citrinum. It is the first report of their production from 1 by using A. niger and P. citrinum with complete <SUP>1</SUP>H- and <SUP>13</SUP>C-NMR assignment. The structures of both metabolites were characterized by various spectroscopic techniques and reported data.
목차
Abstract
Introduction
Experimental
Result and Discussion
References
참고문헌 (14)
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