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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 222 - 226 (5page)
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초록· 키워드
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Flavonoids including quercetin and rutin are a group of naturally occurring compounds widely distributed in plants, especially in buckwheat. Thus, cereal and the leaf of the plant have increasingly used as a source of nutritional and functional foods such as noodle, cake or soup in Korea, Japan and other countries. This study investigated comparative effects of dietary rutin rich in buckwheat and its aglycone, quercetin, on serum biomarkers and antioxidant parameters in rats treated with chronic ethanol. Rats were fed with the liquid diets prepared by the method of Lieber Decarli. Serum alanine transaminase (ALT) and aspartate transaminase (AST) activities increased significantly by alcohol feeding. Dietary flavonoids including rutin, quercetin and their mixtures (1/1, v/v) decreased significantly the activities of serum ALT whereas the feeding of quercetin decreased only the activity of serum AST. The concentration of serum malondialdehydes elevated by chronic alcohol feeding decreased markedly in all the experimental groups that were fed with the flavonoids; however, the combined administration of quercetin or rutin, but not that of rutin or quercetin alone decreased significantly the concentration of liver malondialdehydes to the normal range in rats fed without ethanol. Our results suggested that dietary combined mixture of rutin and quercetin might be effective in ameliorating adverse responses seen in rats exposed to ethanol chronically.
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참고문헌 (24)
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Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents
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Preventive and Therapeutic Effects of Quercetin on Experimental Radiation Induced Lung Injury in Mice
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Direct vascular actions of quercetin in aorta from renal hypertensive rats
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Effect of Rutin on Diabetic Auditory Neuropathy in an Experimental Rat Model
Clinical and Experimental Otorhinolaryngology
2021 .08
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Rutin induces autophagy in cancer cells
International Journal of Oral Biology
2016 .01
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Influence of rutin on the effects of neonatal cigarette smoke exposure-induced exacerbated MMP-9 expression, Th17 cytokines and NF-κB/iNOS-mediated inflammatory responses in asthmatic mice model
The Korean Journal of Physiology & Pharmacology
2018 .09
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Autophagy Inhibition Promotes Quercetin Induced Apoptosis in MG-63 Human Osteosarcoma cells
International Journal of Oral Biology
2015 .01
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Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain Injury
대한신경외과학회지
2017 .01
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Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity
The Korean Journal of Physiology & Pharmacology
2017 .03
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Quercetin Upregulates Uncoupling Protein 1 in White/Brown Adipose Tissues through Sympathetic Stimulation
Journal of Obesity & Metabolic Syndrome
2018 .01
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Quercetin Directly Interacts with Vitamin D Receptor (VDR): Structural Implication of VDR Activation by Quercetin
Biomolecules & Therapeutics(구 응용약물학회지)
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Quercetin induces cell death by caspase-dependent and p38 MAPK pathway in EGFR mutant lung cancer cells
고신대학교 의과대학 학술지
2016 .01
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Treatment with Rutin - A Therapeutic Strategy for Neutrophil-Mediated Inflammatory and Autoimmune Diseases - Anti-inflammatory Effects of Rutin on Neutrophils -
Journal of Pharmacopuncture
2017 .01
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HepG2 cell에서 quercetin의 HO-1 발현을 통한 mitochondria의 생합성 유도 효과에 관한 연구
대한한의정보학회지
2015 .01
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Modulation of the Expression of the GABAA Receptor β1 and β3 Subunits by Pretreatment with Quercetin in the KA Model of Epilepsy in Mice
Journal of Pharmacopuncture
2016 .01
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Effect of proton beam irradiation on cytotoxicity and anti-inflammatory activity of quercetin
한국실험동물학회 학술발표대회 논문집
2016 .08
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Content Analysis of Rutin in the Leaves of Boehmeria nivea Harvested in Different Regions of South Korea by HPLC-UV
Natural Product Sciences
2018 .03
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Quercetin attenuates neuronal cells damage in a middle cerebral artery occlusion animal model and HT-22 cells
한국실험동물학회 학술발표대회 논문집
2018 .07
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Quercetin reduces the injury-induced reduction of γ-enolase expression in a middle cerebral artery occlusion animal model
한국실험동물학회 학술발표대회 논문집
2018 .07
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Effect of quercetin on the anti-tumor activity of cisplatin in EMT6 breast tumor-bearing mice
Obstetrics & Gynecology Science
2019 .01
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