지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 262 - 267 (6page)
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이 논문의 연구 히스토리 (3)
2014
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초록· 키워드
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Royal jelly composes of many components, especially protein. Protein is a major factor which cause allergy. We focused on water soluble royal jelly (WSRJ) that was removed allergy - inducing protein. 10-hyroxy-2-decenoic acid content of WSRJ is 2.42 g/100 g, which is double compared to that of lypophilized RJ. To further access WSRJ as a cosmetic ingredient and potential external treatment for topical use, we investigated its ability to inhibit tyrosinase activity and melanin biosynthesis on melanogenesis in B16F1 melanoma cells. We found that WSRJ increased the cell viability in B16F1 melanoma cell and WSRJ (1~10 mg/ml) inhibited melanin synthesis in with 10 nM α-melanocyte-stimulating hormone (α-MSH) for 48 h. WSRJ inhibited direct tyrosinase activity, which decreased melanin synthesis in α-MSH stimulated B16F1 melanoma cells. Thease findings suggest that WSRJ induces the down regulation of melanogenesis by inhibiting tyrosinase activation.
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참고문헌 (28)
참고문헌 신청
Fujiwara, S. / 1990 / A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin / J. Biol. Chem 265:11333~11337
Nagai, T. / 2004 / Preparation and the functional properties of water extract and alkaline extract of royal jelly / Food Chem 84:181~186
Santos, C. C. / 2007 / Quantitative determination of trans-10-Hydroxy-2-Decenoic Acid (10-HDA) in Brazilian royal jelly and commercial products containing royal jelly / J. Apicult. Res 46:149~153
Sabatini, A. G. / 2009 / Quality and satndardisation of royal jelly / J. ApiProd. ApiMed. Sci 1:1~6
Krell, R. / 1996 / Value-added products from beekeeping / FAO Food and Agriculture Organization of the United Nations Rome :409
Nagai, T. / 2004 / Preparation and the functional properties of water extract and alkaline extract of royal jelly / Food Chem 84:181~186
Santos, C. C. / 2007 / Quantitative determination of trans-10-Hydroxy-2-Decenoic Acid (10-HDA) in Brazilian royal jelly and commercial products containing royal jelly / J. Apicult. Res 46:149~153
Sabatini, A. G. / 2009 / Quality and satndardisation of royal jelly / J. ApiProd. ApiMed. Sci 1:1~6
Krell, R. / 1996 / Value-added products from beekeeping / FAO Food and Agriculture Organization of the United Nations Rome :409
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