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자료유형
학술저널
저자정보
저널정보
한국생약학회 생약학회지(Korean Journal of Pharmacognosy) 생약학회지 제33권 제4호
발행연도
2002.12
수록면
364 - 371 (8page)

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Yew (Taxus cuspidata Sieb) selected cultivation as drug, food and decorative plant in Gyong-gi province in Korea. To extract the water soluble active ingredients, as a extracting method, there was extracted with 20 g of dried seeds with each 20g of butylene glycol(BG) and propylene glycol(PG), and 40 mL of water mixing 72 hours at 40±0.5℃, and then they were filtrated by 400 mesh. Appearance of extract of seeds was pale brown, pH=4.5±0.5℃, gravity= 1.013±0.5℃, a reflective index= 1.373±0.5℃, and yield=75%. Also, to extract the high purity oil from seeds, it minutely pulverized the dried seeds and added the hexane, mixing 2 hours at 20±0.5℃. And then, this filtrated it with 400-mesh. It got the purified oil through evaporating them at 55℃ during under vacuum. As the results, appearance was slightly brown, gravity=0.922 acid value=0.12, saponification value=192, and it should be obtained the 40±0.5℃ of yield. As the efficacy evalution of cosmetic field, the antioxidative activities by NBT method were stronger 86.0% from extract of taxus seeds than 52.0% from green tea extract and 35.0% from skullcap extract as well as the antioxidative activities by DPPH method were stronger 93.7% from extract of seed than 60.3% from extract of green tea and 27.1 % from extract of skullcap. These are more effective than other plant extracts. The collagen synthesis rate on the activating fibroblast for Taxus cuspidata Sieb extract showed 35.43%. As the activity of the skin elasticity, PPE(porcine pancreatic elastase)-inhibitory activities of taxus extract was 50.8%. Anti-inflammatory activity was more effective to be taken 41.1 % of taxus seed oil than 24.2% of steady glycyrrhetinate (SG) as a control.

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