하부 직장암에서 괄약근보존술과 복회음절제술의 장기적 종양학적 결과

정상훈; 유창식; 최평화; 김대동; 홍동현; 김희철; 김진천

추천

검색

자료유형: 학술저널

저자정보: 정상훈 (울산대학교) 유창식 (울산대학교) 최평화 (울산대학교) 김대동 (울산대학교) 홍동현 (울산대학교) 김희철 (울산대학교) 김진천 (울산대학교)

저널정보: 대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy Vol.23 No.3

발행연도: 2007.1

수록면: 186 - 193 (8page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

이 논문의 연구 히스토리 (2)

2007

하부 직장암에서 괄약근보존술과 복회음절제술의 장기적 종양학적 결과

정상훈 , 유창식 , 최평화 외 4명 Annals of Coloproctology 2007.01 학술저널

2006

하부 직장암 수술 시 복회음절제술이 시행된 군이 괄약근보존술이 시행된 군에 비해 예후가 더 나쁜가?

정상훈 , 유창식 , 김대동 외 3명 대한외과학회 학술대회 초록집 2006.05 학술대회자료

이 논문의 후속연구가 궁금하신가요?
연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
이 논문의 연구 히스토리 확인하기

초록· 키워드

오류제보하기

Purpose: The oncological safety of a sphincter-saving resection (SSR) in lower rectal cancer is widely accepted, and both an abdominoperineal resection (APR) and a SSR are used in potentially curative surgery. This retrospective study was performed to compare the long-term oncological outcomes after an APR and a SSR in patients with lower rectal cancer (within 5 cm from the anal verge). Methods: We recruited 441 lower rectal cancer patients who underwent curative resections (APR: 305, SSR: 136) between 1995 and 2000. A total mesorectal excision and autonomic nerve preservation were routinely performed. The median follow- up period was 65 months. Results: Most demographic findings were comparable between the groups; however, the APR groups revealed more advanced pathological characteristics (tumor depth, size, cell differentiation, and metastatic LN number). The local recurrence rates after an APR and a SSR were 12.8% and 7.4%, respectively (P= 0.09). An independent risk factor of local recurrence was LN metastasis only. Distant recurrence was higher in the APR group (26.4%) than in the SSR group (13.2%), but on multivariate analysis the difference was not significant (P=0.17). The 5-year cancer-specific survival rates after an APR and a SSR were 73.2% and 87.6%, respectively (P＜0.05). Particularly, there was a significant survival difference for stage III patients (APR: 59.0% vs. SSR: 83.0%, P＜0.05). However, an APR was not an independent prognostic factor for cancer-specific survival in the multivariate analysis (P=0.07). Conclusions: An APR per se did not influence local recurrence after a curative resection for lower rectal cancer. The poor cancer-specific survival in the stage III APR group might be attributed to increased distant metastasis due to its more distal location.

#Sphincter-saving resection #Abdominoperineal resection #Recurrence #Survival rate

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요