지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 97 - 102 (6page)
이용수
초록· 키워드
오류제보하기
Portal vein thrombosis (PVT) is a clinical situation that usually begins at the extrahepatic portal vein and sometimes extends into the intrahepatic portal vein, or distally to the superior mesenteric and splenic veins.
The clinical presentation (asymptomatic to fatal bowel ischemia) and etiology (liver cirrhosis, systemic cause such as hypercoagulable state and myeloproliferative diseases, local cause such as acute appendicitis) is so diverse that the clinical decision making is sometimes very difficult. When the thrombus extends into the superior mesenteric vein, bowel ischemia and infarction should be anticipated and prevented cautiously with immediate initiation of anticoagulant therapy. The most troublesome chronic sequelae of the portal vein thrombosis is portal vein hypertension, which deteriorates patients’ quality of life. The goal of treatment is to prevent ischemic bowel infarction and portal vein hypertension. Color Doppler sonography, computed tomography, and magnetic resonance imaging are convenient diagnostic tools to confirm PVT. The systemic thrombotic state or cause of infection must be determined through serologic studies. It is helpful to divide PVT patients into cirrhotic and non-cirrhotic, acute and chronic patients. In cases of non-cirrhotic acute PVT,rapid correction of the systemic and local cause of thrombosis and early initiation of anticoagulant therapy are considered the gold standard of treatment. In cases of cirrhotic and chronic PVT, the risk of bleeding and the efficiency of anticoagulation therapy should be measured and balanced for each patient. This article discusses the debated issue of the various treatment paradigms for PVT.
목차
등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
Jang JY / 2010 / Clinical experience of mesenteric vascular diseases and management / J Korean Soc Vasc Surg 26:162~168
Okuda K / 1985 / Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients / Gastroenterology 89:279~286
Amitrano L / 2004 / Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis / J Hepatol 40:736~741
Joo Dong Kim / 2011 / An early single-center experience of portal vein thrombosis in living donor liver transplantation: clinical feature, management and outcome / 대한외과학회지 81(1):35~42
Mangia A / 2005 / Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors / Eur J Gastroenterol Hepatol 17:745~751
Okuda K / 1985 / Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients / Gastroenterology 89:279~286
Amitrano L / 2004 / Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis / J Hepatol 40:736~741
Joo Dong Kim / 2011 / An early single-center experience of portal vein thrombosis in living donor liver transplantation: clinical feature, management and outcome / 대한외과학회지 81(1):35~42
Mangia A / 2005 / Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors / Eur J Gastroenterol Hepatol 17:745~751
이 논문의 저자 정보
최근 본 자료
댓글(0)
0