We experienced a rare case of acute myocardial infarction associated with a coagulopathy-complicating snake bite. A previously healthy 72-year-old Korean woman was bitten on the right thumb by a snake of unknown species. She was admitted to a local medical center for one day and exhibited painful progressive swelling along the entire right arm. She also complained of chest discomfort. She had an ST-elevation and T wave-inversion on an ECG. She was then transferred to our emergency department. We found a regional wall motion abnormality on echocardiography, and elevated cardiac enzymes in a laboratory test. We also observed coagulopathy and a thrombus in the left ventricle on follow-up echocardiography. An acute myocardial infarction was confirmed by percutaneous coronary angiography, which showed the total occlusion and stenosis of several coronary arteries.