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자료유형
학술저널
저자정보
저널정보
대한스포츠의학회 대한스포츠의학회지 대한스포츠의학회지 제27권 제2호
발행연도
2009.1
수록면
192 - 199 (8page)

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This research is about the effect of 4 weeks’ resistive exercise on IGF-1 and UCP-3, where they are known for major muscle effecting genes and having effects on tissue growth & development, and body metabolism. Twenty-four male Sprague-Dawley rats were included at 10 wks of age and assigned into control group (CG) and resistance exercise group (EG). After 4-weeks of resistance exercise, the total RNA of each group was separated. And qPCR was used to analyze RNA quantitatively. After 4-weeks of regulated resistance exercise, there was statistical difference in IGF-1 and UCP-3 mRNA expression (p<0.001) in skeleton muscles between the control group and the resistance exercise group. At post-hoc, EG had significantly higher IGF-1 and UCP-3 mRNA expression than CG (p<0.01; p<0.001) and the 4th week CG (p<0.001; p<0.001). In conclusion, the resistance exercise increased IGF-1 mRNA expression in the skeleton muscle, and after the experiment there was significant increase in UCP-3 mRNA expression as well.

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