지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 19 - 25 (7page)
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초록· 키워드
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Background and Objectives: Patients with Ménière’s disease often present with a great variety of symptoms, especially at the onset of the disease. However, there is no single test that is definitive for making the diagnosis of Ménière’s disease.
Recently, a new diagnostic test, the cochlear hydrops analysis masking procedure (CHAMP) was introduced as a test for endolymphatic hydrops. The aim of this study is to evaluate the diagnostic value of CHAMP test in Ménière’s disease in comparison with that of electrocochleography. Materials and Methods: The CHAMP test and electrocochleography were simultaneously performed in 14 cases of definite Ménière’s disease and 8 normal healthy volunteers (16 ears). Positive criteria were defined as being more than 0.35 in summating potential/action potential (SP/AP)ratio, 0.3 ms or less in latency delay and 0.95 or less in complex amplitude ratio.
Measured parameters from each test were compared between the groups, and sensitivity and specificity of each test in diagnosing Ménière’s disease were calculated. Results: There was no significant difference in the SP/AP ratio of electrocochleography between the Ménière’s disease and control groups. In CHAMP test, the latency delay was shorter and the complex amplitude ratio was smaller (p<0.001). While taking positive results from both test parameters, the sensitivity and specificity of CHAMP test were 85.7% and 87.5%, respectively. Conclusion:The CHAMP seems to be a clinically useful tool in diagnosing Ménière’s disease and might be better than electrocochleography to detect endolymphatic hydrops.
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