지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 1,024 - 1,030 (7page)
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초록· 키워드
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Atopic myelitis is defined as myelitis with atopic diasthesis but the cause is still unknown.
Toxocariasis is one of the common causes of hyperIgEaemia that may lead
to neurologic manifestations. The purpose of this study was to evaluate the sero-prevalence
of Toxocara specific IgG Ab among the atopic myelitis patients. We evaluated
the medical records of 37 patients with atopic myelitis whose conditions were
diagnosed between March 2001 and August 2007. Among them, the 33 sera were
analyzed for specific serum IgG Ab to Toxocara excretory-secretory antigens (TES).
All of 37 patients had hyperIgEaemia. Specific IgE to D. pteronyssinus and D. farinae
was detected in 22 (64.7%) and 34 (100%) patients, respectively, of the 34 patients.
Thirty-one of 33 patients (93.9%) were found to be positive by TES IgG enzymelinked
immunosorbent assay (ELISA). Based on the image findings of eosinophilic
infiltrations in the lung and liver, 8 patients had positive results. These results inferred
that the prevalence of toxocariasis was high in patients with atopic myelitis. Our results
suggest that toxocariasis might be an important cause of atopic myelitis and Toxocara
ELISA is essential for evaluating the causes of atopic myelitis.
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