지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 632 - 635 (4page)
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초록· 키워드
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We evaluated the clinical usefulness of simultaneous LISS/Coombs and NaCl/Enzyme
testing using the gel method for screening and identification of unexpected antibodies
in 15,014 samples. When unexpected antibodies were detected by either screening
test, those antibodies were identified using both the LISS/Coombs and the NaCl/
Enzyme gel test. The positive screening rates of the LISS/Coombs, NaCl/Enzyme,
and combined tests (excluding 25 autoantibody cases) were 0.48%, 1.29%, and
1.39%, respectively. Among the 57 samples positive by both screening methods,
the antibodies in 19.3% could be identified only by the NaCl/Enzyme method. Among
the 137 samples positive only by NaCl/Enzyme screening, 74.5% showed positive
results in antibody identification only by the NaCl/Enzyme test, although 7.3% were
also positive in the LISS/Coombs test. The NaCl/Enzyme method thus showed about
threefold higher detection rates than the LISS/Coombs method, especially in screening
for Rh antibodies, and higher exact identification rates and discriminatory power
for identifying mixed antibodies. Addition of the NaCl/Enzyme method to routine
laboratory procedures may detect and identify considerable numbers of significant
antibodies that might be missed if only the LISS/Coombs method is used.
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