지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 40 - 45 (6page)
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초록· 키워드
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Toxocariasis is one of the causes of pulmonary eosinophilic infiltrate that is increasing in Korea. This study was designed to identify the prevalence of toxocara seropositivity in patients with unexplained pulmonary patchy infiltrate and to evaluate associated factors. We evaluated 102 patients with unexplained pulmonary patchy infiltrate on chest computed tomography (CT) scan. As a control set, 116 subjects with normal chest CT were also evaluated. History of allergic disease, drug use, parasitic disease and raw cow liver intake were taken. Blood eosinophil count and total IgE level were measured. Specific serum IgG antibody to Toxocara canis larval antigen and specific IgG antibodies to 4 other parasites were measured by enzymelinked immunosorbent assay (ELISA). In the infiltrate group, 66.7% subjects were toxocara seropositive whereas 22.4% of the control group were seropositive (p< 0.001). In the infiltrate group, patients with a history of eating raw cow liver (odds ratio [OR], 7.8) and patients with eosinophilia (OR, 5.2) had a higher incidence of toxocara seropositivity. Thirty-five percent of toxocara seropositive patients with infiltrate exhibited migrating infiltrate and 48% had decreased infiltrate on the follow- up CT. We recommend that toxocara ELISA should be performed in patients with unexplained pulmonary patchy infiltrate, and that the eating of raw cow liver should be actively discouraged.
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참고문헌 (18)
참고문헌 신청
Kaneko M / 1996 / Peripheral lung cancer: screening and detection with low-dose spiral CT scan versus radiography / Radiology 201:798~802
Henschke CI / 2006 / Survival of patients with stage I lung cancer detected on CT scan screening / N Engl J Med 355:1763~1771
김유진 / 2007 / 개회충 유충 감염에서 발생되는 호산구성 폐질환의 특성 / Tuberculosis and Respiratory Diseases 62(1):19~26
Despommier D / 2003 / Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects / Clin Microbiol Rev 16:265~272
Fan CK / 2004 / Seroepidemiology of Toxocara canis infection among mountain aboriginal adults in Taiwan / Am J Trop Med Hyg 71:216~221
Henschke CI / 2006 / Survival of patients with stage I lung cancer detected on CT scan screening / N Engl J Med 355:1763~1771
김유진 / 2007 / 개회충 유충 감염에서 발생되는 호산구성 폐질환의 특성 / Tuberculosis and Respiratory Diseases 62(1):19~26
Despommier D / 2003 / Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects / Clin Microbiol Rev 16:265~272
Fan CK / 2004 / Seroepidemiology of Toxocara canis infection among mountain aboriginal adults in Taiwan / Am J Trop Med Hyg 71:216~221
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