지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 298 - 309 (12page)
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초록· 키워드
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Rheumatoid arthritis refers to acute and chronic arthritis due to unexplained autoantibody attack. Rheumatoid arthritis should be accompanied by difficulty in mobility and severe distress due to the progression of systemic arthritis. Therefore, this study early diagnoses the effects of Rheumatoid factor (RF), C-reactive protein (CRP), and Anti-cyclic citrullinated peptide (Anti-CCP), which are typical serum markers for rheumatoid arthritis by meta-analysis. Pubmed and EMBASE, were used as PICO criteria, and two independent researchers selected papers according to the criteria set in this study. The selection criteria was a study of patients with rheumatoid arthritis who developed early onset, and the paper was evaluated using the NCS. Forest plot and Funnel plot graphs for each serum marker were calculated using Revman 5.4. After finding 193 papers on Pubmed and 184 papers on EMBASE and selecting according to the criteria, a total of 41 papers were used for the analysis. The magnitude of the effect that appears in the Forest plot of RF with the Mean difference value is 134.34, CRP is 21.42 and Anti-CCP is 270.41. The magnitude of the effect of Anti-CCP in meta-analysis was analyzed to be larger than that of RF and CRP, and it is considered that the development of early-diagnosis serum markers using Anti-CCP and additional retrospective studies are highly effective. The combination of RF, CRP, and Anti-CCP as a panel marker is expected to be very efficient.
목차
서론
재료 및 방법
결과
고찰
REFERENCES
참고문헌 (51)
참고문헌 신청
Abdul-Maksoud RS / 2017 / Serum miR-210 and miR-155 expression levels as novel biomarkers for rheumatoid arthritis diagnosis / Br J Biomed Sci 74:209~213
Åhlin E / 2015 / Anti-Citrullinated Peptide Antibodies in Sudanese Patients with Leishmania donovani Infection Exhibit Reactivity not Dependent on Citrullination / Scandinavian Journal of Immunology 81:201~208
Aiman AQ / 2020 / A new tool for early diagnosis of rheumatoid arthritis using combined biomarkers;synovial MAGE-1 mRNA and serum anti-CCP and RF / Pan Afr Med J 36:270
Aletaha D / 2010 / 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative / Arthritis & Rheumatism 62:2569~2581
Anaparti V / 2019 / Circulating levels of free 25(OH)D increase at the onset of rheumatoid arthritis / PLoS One 14:0219109
Åhlin E / 2015 / Anti-Citrullinated Peptide Antibodies in Sudanese Patients with Leishmania donovani Infection Exhibit Reactivity not Dependent on Citrullination / Scandinavian Journal of Immunology 81:201~208
Aiman AQ / 2020 / A new tool for early diagnosis of rheumatoid arthritis using combined biomarkers;synovial MAGE-1 mRNA and serum anti-CCP and RF / Pan Afr Med J 36:270
Aletaha D / 2010 / 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative / Arthritis & Rheumatism 62:2569~2581
Anaparti V / 2019 / Circulating levels of free 25(OH)D increase at the onset of rheumatoid arthritis / PLoS One 14:0219109
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UCI(KEPA) : I410-ECN-0101-2022-510-000141809