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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 231 - 238 (8page)
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초록· 키워드
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Several structural proteins present in keratinocytes of the skin are known to play an important role in the formation of epidermal tissue and barrier function, and the absence of structural proteins in keratinocytes causes various skin diseases. In this study, 42 types of tetrapeptides derived from the sequence of Loricrin, a kind of terminally differentiating structural protein, were synthesized, and skin anti-aging properties were measured by measuring the elastase inhibition, proliferation of skin cells. The anti-aging efficacy was verified and, based on this, it succeeded in selecting one of the most excellent peptides. It is expected that the selected tetrapeptide can be used as a raw material for various cosmetics and quasi-drugs based on anti-aging and skin cell proliferation effects.
목차
서론
재료 및 방법
결과 및 고찰
REFERENCES
참고문헌 (21)
참고문헌 신청
Bayer E / 1986 / Chemistry of peptides and Proteins / de Gryyter :3~8
Bergmann M / 1932 / Über ein allgemeines Verfahren der Peptid-Synthese / Berichte der deutschen chemischen Gesellschaft(A and B Series) 65:1192~1201
Carpino LA / 1970 / 9-Fluorenylmethoxycarbonyl function, a new base-sensitive amino-protecting group / Am Chem Soc 92:5748~5749
Chang CD / 1978 / Solid-phase peptide synthesis using mild base cleavage of Nα-fluorenylmethyloxycarbonylamino acids, exemplified by a synthesis of dihydrosomatostatin / Int J Pept Protein Res 11:246~249
Cho YH / 2005 / Effect of etyl acetate fraction from melothria heterophylla on antioxidant activity and metrix metalloproteinase-1 expression in ultraviolet-A irradiated human dermal fibroblast / J Soc Cosmet Sci Kor 31:103~109
Bergmann M / 1932 / Über ein allgemeines Verfahren der Peptid-Synthese / Berichte der deutschen chemischen Gesellschaft(A and B Series) 65:1192~1201
Carpino LA / 1970 / 9-Fluorenylmethoxycarbonyl function, a new base-sensitive amino-protecting group / Am Chem Soc 92:5748~5749
Chang CD / 1978 / Solid-phase peptide synthesis using mild base cleavage of Nα-fluorenylmethyloxycarbonylamino acids, exemplified by a synthesis of dihydrosomatostatin / Int J Pept Protein Res 11:246~249
Cho YH / 2005 / Effect of etyl acetate fraction from melothria heterophylla on antioxidant activity and metrix metalloproteinase-1 expression in ultraviolet-A irradiated human dermal fibroblast / J Soc Cosmet Sci Kor 31:103~109
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UCI(KEPA) : I410-ECN-0101-2022-510-000141718