지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 194 - 204 (11page)
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초록· 키워드
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Patients with inflammatory bowel disease (IBD) are at an increased risk of developing colorectal cancer (CRC), and key contributing factors include chronic colonic inflammation and the extent and duration of disease. This increase in risk is more likely to result from chronic inflammation of the colonic mucosa than from any clearly defined genetic predisposition. However, globally, the true magnitude of this risk is debatable, since results from different studies are heterogeneous in terms of geographical and methodological variables. The prevalence of IBD-related CRC in the Asia-Pacific region ranges from 0.3% to 1.8% and a recent study found that the cumulative incidence of IBD-related CRC is comparable to that in Western countries. However, the CRC mortality rate in the Asia-Pacific region is on the rise compared with that in Western countries, and a few Asian countries show particularly rapid upward trends in CRC incidence. Although our understanding of the molecular and clinical basis for IBD-related CRC has improved substantially, our means of prevention, endoscopic surveillance, chemoprevention, and prophylactic surgery remain modest at best. Furthermore, published data on IBD-related CRC in the Asia-Pacific region is lacking, and this review addresses many aspects including epidemiology, natural history, etiopathogenesis, morphology, and biological behaviors of IBD-related CRC and sporadic CRC in the Asia-Pacific region. In this review, we will also discuss the risk factors for CRC in IBD patients, endoscopic technology screening, and surveillance programs and management strategies for IBD-related CRC.
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참고문헌 (85)
참고문헌 신청
Yang SK / 2008 / Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: a KASID study / Inflamm Bowel Dis 14:542~549
Yao T / 2000 / Crohn’s disease in Japan: diagnostic criteria and epidemiology / Dis Colon Rectum 43:S85~S93
Lok KH / 2008 / Epidemiology and clinical characteristics of ulcerative colitis in Chinese population : experience from a single center in Hong Kong / J Gastroenterol Hepatol 23:406~410
Thia KT / 2006 / Crohn’s disease runs a more aggressive course in young Asian patients / Inflamm Bowel Dis 12:57~61
Kitahora T / 1995 / Epidemiological study of ulcerative colitis in Japan: incidence and familial occurrence. The Epidemiology Group of the Research Committee of Inflammatory Bowel Disease in Japan / J Gastroenterol 30(Suppl 8):5~8
Yao T / 2000 / Crohn’s disease in Japan: diagnostic criteria and epidemiology / Dis Colon Rectum 43:S85~S93
Lok KH / 2008 / Epidemiology and clinical characteristics of ulcerative colitis in Chinese population : experience from a single center in Hong Kong / J Gastroenterol Hepatol 23:406~410
Thia KT / 2006 / Crohn’s disease runs a more aggressive course in young Asian patients / Inflamm Bowel Dis 12:57~61
Kitahora T / 1995 / Epidemiological study of ulcerative colitis in Japan: incidence and familial occurrence. The Epidemiology Group of the Research Committee of Inflammatory Bowel Disease in Japan / J Gastroenterol 30(Suppl 8):5~8
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