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Behavioral problems could be easily observed in patients with various mental disorders. Self-injurious behavior (SIB) can be defined as deliberated harm to one’s own body without conscious suicidal intent. It usually occurs as head banging or hitting, body hitting, skin cutting, or finger biting. Also it frequently involves oral tissue’s damage in pediatric patients, such as lip, cheek and tongue biting. Various articles have described prostheses used to prevent SIB-related injuries to the oral tissues of patients who have developmental or medical problems, such as psychological problems, congenital syndromes or mental retardation. But reports of oral SIB in individuals unaffected by the above conditions are scarce. The case presented in this report discusses oral SIB in a premature baby. We found an optimal way that would prevent SIB-related injuries and also protect the causative teeth. These days, dentists should be able to manage those patients with several treatment modalities, furthermore, to prevent SIB according to the causative disorders.

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