지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.20 No.4
- 발행연도
- 2014.1
- 수록면
- 531 - 538 (8page)
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초록· 키워드
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Background/Aims Data on frequency of fecal evacuation disorder (FED) among patients with solitary rectal ulcer syndrome (SRUS), hitherto an enigmatic condition, are scanty. Moreover, most such studies had limitations due to small sample size and lack of inclusion of healthy controls (HC).
Methods Forty patients with SRUS underwent symptom assessments, sigmoidoscopy, anorectal manometry, defecography, balloon expulsion test (BET); endoscopic ultrasound (EUS) of anal sphincter complex was performed in a subgroup. Physiological tests (anorectal manometry and BET) were also performed in 19 HC.
Results Patients with SRUS (26/40 male, age 37 [18-80] years) more often had FED than HC (10/19 male, age 43 [25-72] years) as shown by weight needed to expel the balloon (300 [0-700] g vs. 100 [0-400] g; P = 0.006), a trend towards abnormal BET (need of ＞ 200 g weight for expulsion) (21/40 [53%] vs. 5/19 [26%], P = 0.058) and impaired anal relaxation (14/40 [35%] vs 2/19 [10.5%]; P = 0.048). Using Rome III criteria, most patients with SRUS reported having chronic constipation (36/40 [90%]) in spite of having normal (Bristol stool type IV, 21/40 [53%]) and diarrheal (types V, VI, VII, 6/40 [20%]) stool forms (Asian classification). SRUS patients more often (17/40 [43%]) had functional defecation disorder (Rome III criteria). Patients with SRUS with abnormal BET had thicker internal anal sphincter than those without (3.9 [3.4-7.0] mm vs 2.8 [2.0-4.0] mm; P = 0.01).
Conclusions FED was commoner among patients with SRUS as evidenced by abnormal BET and sphincter relaxation. Those with abnormal BET had thicker internal sphincter on EUS than those without.
목차
등록된 정보가 없습니다.
참고문헌 (42)
참고문헌 신청
Ertem D / 2002 / A rare and often unrecognized cause of hematochezia and tenesmus in childhood: solitary rectal ulcer syndrome / Pediatrics 110:e79
Sun WM / 1989 / A common pathophysiology for full thickness rectal prolapse, anterior mucosal prolapse and solitary rectal ulcer / Br J Surg 76:290~295
Vaizey CJ / 1998 / Solitary rectal ulcer syndrome / Br J Surg 85:1617~1623
Sitzler PJ / 1998 / Long-term clinical outcome of surgery for solitary rectal ulcer syndrome / Br J Surg 85:1246~1250
Rao SS / 1997 / How useful are manometric tests of anorectal function in the management of defecation disorders? / Am J Gastroenterol 92:469~475
Sun WM / 1989 / A common pathophysiology for full thickness rectal prolapse, anterior mucosal prolapse and solitary rectal ulcer / Br J Surg 76:290~295
Vaizey CJ / 1998 / Solitary rectal ulcer syndrome / Br J Surg 85:1617~1623
Sitzler PJ / 1998 / Long-term clinical outcome of surgery for solitary rectal ulcer syndrome / Br J Surg 85:1246~1250
Rao SS / 1997 / How useful are manometric tests of anorectal function in the management of defecation disorders? / Am J Gastroenterol 92:469~475
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