지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Spica prunellae has been used as a traditional medicine in Asian countries. In the present study, anti-obese and antioxidant activity of Prunellae spica ethanol extract (PSE) was investigated in 3T3-L1 and HepG2 cells. The 50 and 100 μg/mL of PSE treatment for 4 days (Day -2 to Day 2) dose dependently suppressed 3T3-L1 adipogenesis. We further examined the protective activity of PSE against ethanol-induced cell death. While 800 mM ethanol treatment for 24 h induced significant cell death, the PSE treatment significantly protected ethanol-induced cell death. In addition, the anti-oxidative activities of PSE to reduce the oxidative stress induced by AAPH or Cu2+ ions, which are important ROS to release peroxyl and hydroxyl radicals, were observed. These results provide scientific evidence for the development of functional foods using PSE which has anti-obese and antioxidant activities.
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참고문헌 (20)
참고문헌 신청
최준혁 / 2013 / 참취(Aster scaber Thunb.) 추출물의 항산화 효과와 3T3-L1 지방전구세포에서의 지방분화 억제 효과 / 한국식품과학회지 45(3):356~363
정미영 / 2012 / 복부경락마사지와 아로마복부마사지가 여대생의 스트레스, 불안 및 복부비만에 미치는 효과비교 / 아시안뷰티화장품저널 10(3):709~715
Coyle JT / 1983 / Oxidative stress, glutamate, and neurodegenerative disorders / Science 262:689~695
Dorosh NM / 1954 / Phytochemical studies on plants of the Prunella vulgaris variety and of the type of the common meadow geranium. Nauch Studenschesk Obshchestva L'vov / Med. Inst :64~67
Furukawa S / 2004 / Increased oxidative stress in obesity and its impact on metabolic syndrome / J Clin. Invest 114:1752~1761
정미영 / 2012 / 복부경락마사지와 아로마복부마사지가 여대생의 스트레스, 불안 및 복부비만에 미치는 효과비교 / 아시안뷰티화장품저널 10(3):709~715
Coyle JT / 1983 / Oxidative stress, glutamate, and neurodegenerative disorders / Science 262:689~695
Dorosh NM / 1954 / Phytochemical studies on plants of the Prunella vulgaris variety and of the type of the common meadow geranium. Nauch Studenschesk Obshchestva L'vov / Med. Inst :64~67
Furukawa S / 2004 / Increased oxidative stress in obesity and its impact on metabolic syndrome / J Clin. Invest 114:1752~1761
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