지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background:Despite modern advances in laboratory automated medicine, work-process in the blood bank is still handled manually. Several automated immunohematological instruments have been developed and are available in the market. The IH-1000 (Bio-Rad Laboratories, Hercules, CA, USA), a fully automated instrument for immunohematology, was recently introduced. In this study, we evaluated the performance of the IH-1000 for ABO/Rh typing and irregular antibody screening.
Methods:In October 2011, a total of 373 blood samples for ABO/Rh typing and 303 cases for unexpected antibody screening were collected. The IH-1000 was compared to the manual tube and slide methods for ABO/Rh typing and to the microcolumn agglutination method (DiaMed-ID system) for antibody screening.
Results:For ABO/Rh typing, concordance rate was 100%. For unexpected antibody screening, positive results for both column agglutination and IH-1000 were observed in 10 cases (four cases of anti-E and c, three of anti-E, one of anti-D, one of anti-M, and one of anti-Xg) and negative results for both were observed in 289 cases. The concordance rate between IH-1000 and column agglutination was 98.7%. Sensitivity and specificity were 90.9% and 99.3%, respectively.
Conclusion:The automated IH-1000 showed good correlation with the manual tube and slide methods and the microcolumn agglutination method for ABO-RhD typing and irregular antibody screening. The IH-1000 can be used for routine pre-transfusion testing in the blood bank.
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참고문헌 (15)
참고문헌 신청
Han KS / 2006 / Transfusion medicine. 3rd ed / Korea Medical Book Publisher :275~282
Storry JR / 2011 / International Society of Blood Transfusion Working Party on red cell immunogenetics and blood group terminology: Berlin report / Vox Sang 101:77~82
Kim KH / 2007 / Characteristics of RBC alloimmunization detected by unexpected antibody screening tests / Korean J Blood Transfus 18:159~168
Park TS / 2005 / The frequency and clinical significance of delayed serological transfusion reactions in Korean population / Korean J Blood Transfus 16:20~31
Jung TK / 2001 / Unexpected antibody positivity with the use of the LISS/Coombs gel test / Korean J Clin Pathol 21:422~425
Storry JR / 2011 / International Society of Blood Transfusion Working Party on red cell immunogenetics and blood group terminology: Berlin report / Vox Sang 101:77~82
Kim KH / 2007 / Characteristics of RBC alloimmunization detected by unexpected antibody screening tests / Korean J Blood Transfus 18:159~168
Park TS / 2005 / The frequency and clinical significance of delayed serological transfusion reactions in Korean population / Korean J Blood Transfus 16:20~31
Jung TK / 2001 / Unexpected antibody positivity with the use of the LISS/Coombs gel test / Korean J Clin Pathol 21:422~425
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