지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 481 - 488 (8page)
이용수
초록· 키워드
오류제보하기
Background: The Modality of Insulin Treatment Evaluation (MOTIV) study was performed to provide real-world data concerning insulin initiation in Korean type 2 diabetes mellitus (T2DM) patients with inadequate glycemic control with oral hypoglycemic agents (OHAs). Methods: This multicenter, non-interventional, prospective, observational study enrolled T2DM patients with inadequate glycemic control (glycosylated hemoglobin [HbA1c] ≥7.0%) who had been on OHAs for ≥3 months and were already decided to introduce basal insulin by their physician prior to the start of the study. All treatment decisions were at the physician’s discretion to reflect real-world practice. Results: A total of 9,196 patients were enrolled, and 8,636 patients were included in the analysis (mean duration of diabetes, 8.9 years; mean HbA1c, 9.2%). Basal insulin plus one OHA was the most frequently (51.0%) used regimen. After 6 months of basal insulin treatment, HbA1c decreased to 7.4% and 44.5% of patients reached HbA1c <7%. Body weight increased from 65.2 kg to 65.5 kg, which was not significant. Meanwhile, there was significant increase in the mean daily insulin dose from 16.9 IU at baseline to 24.5 IU at month 6 (P<0.001). Overall, 17.6% of patients experienced at least one hypoglycemic event. Conclusion: In a real-world setting, the initiation of basal insulin is an effective and well-tolerated treatment option in Korean patients with T2DM who are failing to meet targets with OHA therapy.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Two Cases of Allergy to Insulin in Gestational Diabetes
Endocrinology and Metabolism
2015 .01
-
Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes
Yonsei Medical Journal
2016 .01
-
Insulin Fact Sheet in Type 1 and 2 Diabetes Mellitus and Trends of Antidiabetic Medication Use in Insulin Users with Type 2 Diabetes Mellitus: 2002 to 2019
Diabetes and Metabolism Journal
2023 .03
-
재조합 사람 인슐린에 대한 알레르기반응 1예
Allergy Asthma & Respiratory Diseases
2015 .01
-
History of insulin treatment of pediatric patients with diabetes in Korea
Annals of Pediatirc Endocrinology & Metabolism
2021 .12
-
Assessment of Insulin Secretion and Insulin Resistance in Human
Diabetes and Metabolism Journal
2021 .09
-
A Century of Progress in Diabetes Care with Insulin: A History of Innovations and Foundation for the Future
Diabetes and Metabolism Journal
2021 .09
-
Insulin-siRNA와 human insulin degrading enzyme (hIDE)의 과발현이 당대사에 관여하는 insulin signaling에 미치는 영향
한국실험동물학회 학술발표대회 논문집
2015 .02
-
Effect of the Concomitant Use of Subcutaneous Basal Insulin and Intravenous Insulin Infusion in the Treatment of Severe Hyperglycemic Patients
Endocrinology and Metabolism
2022 .06
-
The durability and effectiveness of sensor-augmented insulin pump therapy in pediatric and young adult patients with type 1 diabetes
Annals of Pediatirc Endocrinology & Metabolism
2020 .01
-
Dulaglutide as an Effective Replacement for Prandial Insulin in Kidney Transplant Recipients with Type 2 Diabetes Mellitus: A Retrospective Review
Diabetes and Metabolism Journal
2021 .11
-
The Insulin Resistance but Not the Insulin Secretion Parameters Have Changed in the Korean Population during the Last Decade
Diabetes and Metabolism Journal
2015 .01
-
Favorable Glycemic Control with Once-Daily Insulin Degludec/Insulin Aspart after Changing from Basal Insulin in Adults with Type 2 Diabetes
Endocrinology and Metabolism
2019 .01
-
Use of insulin detemir in dogs with diabetes mellitus
Journal of Biomedical and Translational Research
2015 .01
-
The effect of PM10 on insulin resistance by polymorphisms of repair-related genes
환경독성보건학회 심포지엄 및 학술대회
2017 .05
-
Insulin Therapy for Adult Patients with Type 2 Diabetes Mellitus: A Position Statement of the Korean Diabetes Association, 2017
Diabetes and Metabolism Journal
2017 .01
-
Exenatide versus Insulin Lispro Added to Basal Insulin in a Subgroup of Korean Patients with Type 2 Diabetes Mellitus
Diabetes and Metabolism Journal
2017 .01
-
Association between Relative Handgrip Strength and Insulin Resistance in Korean Elderly Men without Diabetes: Findings of the 2015 Korea National Health Nutrition Examination Survey
Korean Journal of Family Medicine
2022 .05
-
Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Patients
Endocrinology and Metabolism
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0